PAK1IP1

PAK1IP1
Identifiers
Aliases	PAK1IP1 , MAK11, PIP1, WDR84, bA421M1.5, hPIP1, PAK1 interacting protein 1
External IDs	OMIM: 607811; MGI: 1915333; HomoloGene: 39574; GeneCards: PAK1IP1; OMA:PAK1IP1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6p24.2 Start 10,694,972 bp [1] End 10,709,782 bp [1]
Gene location (Mouse) Chr. Chromosome 13 (mouse) [2] Band 13|13 A3.3 Start 41,154,499 bp [2] End 41,166,491 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prostate Achilles tendon endometrium islet of Langerhans mucosa of esophagus gonad smooth muscle tissue gastrocnemius muscle monocyte rectum Top expressed in primary oocyte transitional epithelium of urinary bladder otic placode epiblast morula morula maxillary prominence saccule mandibular prominence otic vesicle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component nucleolus nucleus Biological process roof of mouth development negative regulation of signal transduction cell population proliferation ribosomal large subunit biogenesis regulation of signal transduction by p53 class mediator ribosome biogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55003 68083 Ensembl ENSG00000111845 ENSG00000285226 ENSMUSG00000038683 UniProt Q9NWT1 Q9DCE5 RefSeq (mRNA) NM_017906 NM_026550 RefSeq (protein) NP_060376 NP_080826 Location (UCSC) Chr 6: 10.69 – 10.71 Mb Chr 13: 41.15 – 41.17 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

p21-activated protein kinase-interacting protein 1 is an enzyme that in humans is encoded by the PAK1IP1 gene. ^{[5] [6]}

Interactions

PAK1IP1 has been shown to interact with PAK1. ^[5]

References

1. ENSG00000285226 GRCh38: Ensembl release 89: ENSG00000111845, ENSG00000285226 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038683 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Xia C, Ma W, Stafford LJ, Marcus S, Xiong WC, Liu M (May 2001). "Regulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1". Proc Natl Acad Sci U S A. 98 (11): 6174–9. Bibcode:2001PNAS...98.6174X. doi: 10.1073/pnas.101137298 . PMC   33441 . PMID   11371639.
6. "Entrez Gene: PAK1IP1 PAK1 interacting protein 1".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC   133617 . PMID   12429849.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID   14574404.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.