PAN3

PAN3
Identifiers
Aliases	PAN3 , PAN3 poly(A) specific ribonuclease subunit, poly(A) specific ribonuclease subunit PAN3
External IDs	OMIM: 617448; MGI: 1919837; HomoloGene: 6372; GeneCards: PAN3; OMA:PAN3 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	28,295,335 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	147,485,312 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; secondary oocyte; ; thymus; ; trabecular bone; ; epithelium of nasopharynx; ; cerebellar vermis; ; skin of arm; ; mucosa of ileum; ; germinal epithelium; ; corpus epididymis;
	Top expressed in
	zygote; ; secondary oocyte; ; genital tubercle; ; tail of embryo; ; spermatid; ; thymus; ; cerebellar cortex; ; spermatocyte; ; lobe of cerebellum; ; neural layer of retina;
	More reference expression data
	n/a
Gene ontology
Molecular function	poly(A)-specific ribonuclease activity ; protein kinase activity ; nucleotide binding ; protein binding ; ATP binding ; metal ion binding ; RNA binding ;
Cellular component	cytoplasm ; cytosol ; PAN complex ; P-body ;
Biological process	protein phosphorylation ; protein targeting ; mRNA processing ; RNA phosphodiester bond hydrolysis, exonucleolytic ; nuclear-transcribed mRNA poly(A) tail shortening ; deadenylation-dependent decapping of nuclear-transcribed mRNA ; positive regulation of cytoplasmic mRNA processing body assembly ; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ;
	Sources:Amigo / QuickGO
Orthologs
	255967
	72587
	ENSG00000152520
	ENSMUSG00000029647
	Q58A45
	Q640Q5
	NM_175854
	NM_028291 ; NM_001359433
	NP_787050
	NP_082567 ; NP_001346362
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated July 16, 2024

PAN3 poly(A) specific ribonuclease subunit is a protein that in humans is encoded by the PAN3 gene.^[5]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000152520 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029647 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: PAN3 poly(A) specific ribonuclease subunit" . Retrieved 2016-09-27.

PAN3

Related Research Articles

References

Further reading