PAPLN

PAPLN
Identifiers
Aliases	PAPLN , papilin, proteoglycan like sulfated glycoprotein, PPN
External IDs	OMIM: 617785 MGI: 2386139 HomoloGene: 71541 GeneCards: PAPLN
Gene location (Human)
Chr.	Chromosome 14 (human)
End	73,274,640 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	83,792,382 bp
Gene ontology
Molecular function	• peptidase inhibitor activity ; • peptidase activity ; • serine-type endopeptidase inhibitor activity ;
Cellular component	• extracellular region ;
Biological process	• negative regulation of peptidase activity ; • negative regulation of endopeptidase activity ; • proteolysis ;
	Sources:Amigo / QuickGO
Orthologs
	89932
	170721
	ENSG00000100767
	ENSMUSG00000021223
	O95428
	Q9EPX2
	NM_173462 ; NM_001365906 ; NM_001365907
	NM_001205343 ; NM_130887
	NP_775733 ; NP_001352835 ; NP_001352836
	NP_001192272 ; NP_570957
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 05, 2021

Papilin is a protein that in humans is encoded by the PAPLN gene.^[5]^[6]^[7] Papilin is an extracellular matrix glycoprotein.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000100767 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021223 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: papilin".
↑ Kramerova IA, Kawaguchi N, Fessler LI, Nelson RE, Chen Y, Kramerov AA, Kusche-Gullberg M, Kramer JM, Ackley BD, Sieron AL, Prockop DJ, Fessler JH (December 2000). "Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases". Development. 127 (24): 5475–85. doi:10.1242/dev.127.24.5475. PMID 11076767.
↑ Apte SS (November 2009). "A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms". J. Biol. Chem. 284 (46): 31493–7. doi: 10.1074/jbc.R109.052340 . PMC 2797218 . PMID 19734141.

Rose JE, Behm FM, Drgon T, et al. (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464 . PMID 20379614.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697 . PMID 12975309.
Laje G, Allen AS, Akula N, et al. (2009). "Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients". Pharmacogenet. Genomics. 19 (9): 666–74. doi:10.1097/FPC.0b013e32832e4bcd. PMC 2819190 . PMID 19724244.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000100767 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021223 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: papilin".

[pmid11076767-6] Kramerova IA, Kawaguchi N, Fessler LI, Nelson RE, Chen Y, Kramerov AA, Kusche-Gullberg M, Kramer JM, Ackley BD, Sieron AL, Prockop DJ, Fessler JH (December 2000). "Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases". Development. 127 (24): 5475–85. doi:10.1242/dev.127.24.5475. PMID 11076767.

[pmid19734141-7] Apte SS (November 2009). "A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms". J. Biol. Chem. 284 (46): 31493–7. doi: 10.1074/jbc.R109.052340 . PMC 2797218 . PMID 19734141.

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PAPLN

Related Research Articles

References

Further reading