PARP12

PARP12
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2PQF
Identifiers
Aliases	PARP12 , ARTD12, MST109, MSTP109, ZC3H1, ZC3HDC1, poly(ADP-ribose) polymerase family member 12
External IDs	OMIM: 612481; MGI: 2143990; HomoloGene: 11236; GeneCards: PARP12; OMA:PARP12 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7q34 Start 140,023,749 bp [1] End 140,062,951 bp [1]
Gene location (Mouse) Chr. Chromosome 6 (mouse) [2] Band 6|6 B1 Start 39,063,344 bp [2] End 39,095,283 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte granulocyte right lung upper lobe of left lung monocyte spleen mucosa of ileum mucosa of transverse colon rectum tibial nerve Top expressed in zygote secondary oocyte primary oocyte intestinal villus stroma of bone marrow pineal gland mucous cell of stomach left colon jejunum ileum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function NAD+ ADP-ribosyltransferase activity metal ion binding transferase activity RNA binding protein ADP-ribosylase activity Cellular component nucleus Biological process protein auto-ADP-ribosylation protein mono-ADP-ribosylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64761 243771 Ensembl ENSG00000059378 ENSMUSG00000038507 UniProt Q9H0J9 Q8BZ20 RefSeq (mRNA) NM_022750 NM_172893 RefSeq (protein) NP_073587 NP_766481 Location (UCSC) Chr 7: 140.02 – 140.06 Mb Chr 6: 39.06 – 39.1 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Poly [ADP-ribose] polymerase 12 is an enzyme that in humans is encoded by the PARP12 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000059378 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038507 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
6. Katoh M, Katoh M (Jul 2003). "Identification and characterization of human TIPARP gene within the CCNL amplicon at human chromosome 3q25.31". Int J Oncol. 23 (2): 541–7. doi:10.3892/ijo.23.2.541. PMID   12851707.
7. "Entrez Gene: PARP12 poly (ADP-ribose) polymerase family, member 12".

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi: 10.1038/nature01782 . PMID   12853948.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC   2882961 . PMID   12690205.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• <Please add first missing authors to populate metadata.> (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi: 10.1101/gr.8.11.1097 . PMID   9847074.