PCDH1

Last updated
PCDH1
Identifiers
Aliases PCDH1 , PC42, PCDH42, protocadherin 1
External IDs OMIM: 603626 MGI: 104692 HomoloGene: 12613 GeneCards: PCDH1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278613
NM_001278615
NM_002587
NM_032420

NM_029357

RefSeq (protein)

NP_001265542
NP_001265544
NP_002578
NP_115796

n/a

Location (UCSC) Chr 5: 141.85 – 141.88 Mb Chr 18: 38.32 – 38.35 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protocadherin-1 is a protein that in humans is encoded by the PCDH1 gene. [5] [6]

This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracellular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene. [6]

Related Research Articles

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Protocadherin beta-10 is a protein that in humans is encoded by the PCDHB10 gene.

<span class="mw-page-title-main">PCDHGC3</span> Protein-coding gene in the species Homo sapiens

Protocadherin gamma-C3 is a protein that in humans is encoded by the PCDHGC3 gene.

<span class="mw-page-title-main">PCDH8</span>

Protocadherin-8 is a protein that in humans is encoded by the PCDH8 gene.

<span class="mw-page-title-main">PCDHB16</span> Protein-coding gene in the species Homo sapiens

Protocadherin beta-16 is a protein that in humans is encoded by the PCDHB16 gene.

<span class="mw-page-title-main">PCDHB13</span> Protein-coding gene in the species Homo sapiens

Protocadherin beta-13 is a protein that in humans is encoded by the PCDHB13 gene.

<span class="mw-page-title-main">PCDHB5</span> Protein-coding gene in the species Homo sapiens

Protocadherin beta-5 is a protein that in humans is encoded by the PCDHB5 gene.

<span class="mw-page-title-main">PCDH17</span>

Protocadherin-17 is a protein that in humans is encoded by the PCDH17 gene.

<span class="mw-page-title-main">PCDHB11</span> Protein-coding gene in the species Homo sapiens

Protocadherin beta-11 is a protein that in humans is encoded by the PCDHB11 gene.

<span class="mw-page-title-main">PCDHB2</span> Protein-coding gene in the species Homo sapiens

Protocadherin beta-2 is a protein that in humans is encoded by the PCDHB2 gene.

<span class="mw-page-title-main">PCDHA6</span> Protein-coding gene in the species Homo sapiens

Protocadherin alpha-6 is a protein that in humans is encoded by the PCDHA6 gene.

<span class="mw-page-title-main">PCDHA2</span> Protein-coding gene in the species Homo sapiens

Protocadherin alpha-2 is a protein that in humans is encoded by the PCDHA2 gene.

<span class="mw-page-title-main">PCDH10</span>

Protocadherin-10 is a protein that in humans is encoded by the PCDH10 gene.

<span class="mw-page-title-main">PCDHA9</span> Protein-coding gene in the species Homo sapiens

Protocadherin alpha-9 is a protein that in humans is encoded by the PCDHA9 gene.

<span class="mw-page-title-main">PCDH12</span> Protein-coding gene in the species Homo sapiens

Protocadherin-12 is a protein that in humans is encoded by the PCDH12 gene.

<span class="mw-page-title-main">PCDHB9</span> Protein-coding gene in the species Homo sapiens

Protocadherin beta-9 is a protein that in humans is encoded by the PCDHB9 gene.

<span class="mw-page-title-main">PCDH18</span>

Protocadherin-18 is a protein that in humans is encoded by the PCDH18 gene.

<span class="mw-page-title-main">PCDHB15</span> Protein-coding gene in the species Homo sapiens

Protocadherin beta-15 is a protein that in humans is encoded by the PCDHB15 gene.

<span class="mw-page-title-main">PCDHB12</span> Protein-coding gene in humans

Protocadherin beta-12 is a protein that in humans is encoded by the PCDHB12 gene.

<span class="mw-page-title-main">PCDHB3</span> Protein-coding gene in the species Homo sapiens

Protocadherin beta-3 is a protein that in humans is encoded by the PCDHB3 gene.

<span class="mw-page-title-main">PCDH20</span>

Protocadherin-20 is a protein that in humans is encoded by the PCDH20 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000156453 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051375 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Sano K, Tanihara H, Heimark RL, Obata S, Davidson M, St John T, Taketani S, Suzuki S (Jul 1993). "Protocadherins: a large family of cadherin-related molecules in central nervous system". EMBO J. 12 (6): 2249–56. doi:10.1002/j.1460-2075.1993.tb05878.x. PMC   413453 . PMID   8508762.
  6. 1 2 "Entrez Gene: PCDH1 protocadherin 1".

Further reading