PCDH17 | |||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||
Aliases | PCDH17 , PCDH68, PCH68, protocadherin 17 | ||||||||||||||||||||||||
External IDs | OMIM: 611760 MGI: 2684924 HomoloGene: 8700 GeneCards: PCDH17 | ||||||||||||||||||||||||
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Orthologs | |||||||||||||||||||||||||
Species | Human | Mouse | |||||||||||||||||||||||
Entrez | |||||||||||||||||||||||||
Ensembl | |||||||||||||||||||||||||
UniProt |
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RefSeq (mRNA) | |||||||||||||||||||||||||
RefSeq (protein) |
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Location (UCSC) | Chr 13: 57.63 – 57.73 Mb | Chr 14: 84.44 – 84.54 Mb | |||||||||||||||||||||||
PubMed search | [3] | [4] | |||||||||||||||||||||||
Wikidata | |||||||||||||||||||||||||
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Protocadherin-17 is a protein that in humans is encoded by the PCDH17 gene. [5] [6]
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein may play a role in the establishment and function of specific cell-cell connections in the brain. [6] PCDH17 promoter methylation is found to be closely associated with bladder cancer malignancy [7]
Protocadherin beta-10 is a protein that in humans is encoded by the PCDHB10 gene.
Protocadherin-1 is a protein that in humans is encoded by the PCDH1 gene.
Protocadherin gamma-C3 is a protein that in humans is encoded by the PCDHGC3 gene.
Protocadherin-8 is a protein that in humans is encoded by the PCDH8 gene.
Protocadherin beta-13 is a protein that in humans is encoded by the PCDHB13 gene.
Protocadherin beta-5 is a protein that in humans is encoded by the PCDHB5 gene.
Protocadherin beta-2 is a protein that in humans is encoded by the PCDHB2 gene.
Protocadherin alpha-6 is a protein that in humans is encoded by the PCDHA6 gene.
Protocadherin alpha-2 is a protein that in humans is encoded by the PCDHA2 gene.
Protocadherin-10 is a protein that in humans is encoded by the PCDH10 gene.
Protocadherin-12 is a protein that in humans is encoded by the PCDH12 gene.
Protocadherin beta-7 is a protein that in humans is encoded by the PCDHB7 gene.
Protocadherin beta-4 is a protein that in humans is encoded by the PCDHB4 gene.
Protocadherin alpha-5 is a protein that in humans is encoded by the PCDHA5 gene.
Protocadherin-18 is a protein that in humans is encoded by the PCDH18 gene.
Protocadherin gamma-A11 is a protein that in humans is encoded by the PCDHGA11 gene.
Protocadherin beta-15 is a protein that in humans is encoded by the PCDHB15 gene.
Protocadherin alpha-C2 is a protein that in humans is encoded by the PCDHAC2 gene.
Protocadherin alpha-3 is a protein that in humans is encoded by the PCDHA3 gene.
Protocadherin-20 is a protein that in humans is encoded by the PCDH20 gene.