PDZD11

PDZD11
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1WI2
Identifiers
Aliases	PDZD11 , AIPP1, PDZK11, PISP, PDZ domain containing 11
External IDs	OMIM: 300632; MGI: 1919871; HomoloGene: 9530; GeneCards: PDZD11; OMA:PDZD11 - orthologs
Gene location (Human) Chr. X chromosome (human) [1] Band Xq13.1 Start 70,286,595 bp [1] End 70,290,514 bp [1]
Gene location (Mouse) Chr. X chromosome (mouse) [2] Band X|X C3 Start 99,666,489 bp [2] End 99,670,174 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of ileum myocardium of left ventricle parotid gland lateral nuclear group of thalamus hypothalamus prefrontal cortex cardiac muscle tissue of right atrium nasal epithelium substantia nigra amygdala Top expressed in right kidney ventricular zone yolk sac morula choroid plexus of fourth ventricle medial ganglionic eminence blastocyst embryo seminal vesicula embryo More reference expression data BioGPS n/a
Gene ontology Molecular function protein C-terminus binding protein binding Cellular component cytoplasm extracellular region cytosol synapse cell-cell junction presynapse basolateral plasma membrane Biological process maintenance of epithelial cell apical/basal polarity protein localization to basolateral plasma membrane neurotransmitter secretion biotin metabolic process pantothenate metabolic process antimicrobial humoral response ion transmembrane transport transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51248 72621 Ensembl ENSG00000120509 ENSMUSG00000015668 UniProt Q5EBL8 Q9CZG9 RefSeq (mRNA) NM_016484 NM_028303 NM_001356384 RefSeq (protein) NP_057568 NP_001357103 NP_001357104 NP_001357105 NP_001357106 NP_001357107 NP_082579 NP_001343313 Location (UCSC) Chr X: 70.29 – 70.29 Mb Chr X: 99.67 – 99.67 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

PDZ domain-containing protein 11 is a protein that in humans is encoded by the PDZD11 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000120509 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000015668 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC   310934 . PMID   11042152.
6. Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
7. "Entrez Gene: PDZD11 PDZ domain containing 11".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Goellner GM, DeMarco SJ, Strehler EE (2003). "Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants". Ann. N. Y. Acad. Sci. 986 (1): 461–71. Bibcode:2003NYASA.986..461G. doi:10.1111/j.1749-6632.2003.tb07230.x. PMID   12763866. S2CID   447365.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC   2665286 . PMID   15772651.
• Stephenson SE, Dubach D, Lim CM, et al. (2005). "A single PDZ domain protein interacts with the Menkes copper ATPase, ATP7A. A new protein implicated in copper homeostasis". J. Biol. Chem. 280 (39): 33270–9. doi: 10.1074/jbc.M505889200 . hdl: 10536/DRO/DU:30039503 . PMID   16051599.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.