PDZD4

PDZD4
Identifiers
Aliases	PDZD4 , LU1, PDZK4, PDZRN4L, PDZ domain containing 4, LNX5
External IDs	OMIM: 300634 MGI: 2443483 HomoloGene: 13046 GeneCards: PDZD4
Gene location (Human)
Chr.	X chromosome (human)
End	153,830,565 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	72,868,575 bp
RNA expression pattern
	Top expressed in
	cingulate gyrus; ; Brodmann area 9; ; prefrontal cortex; ; amygdala; ; nucleus accumbens; ; caudate nucleus; ; putamen; ; ganglionic eminence; ; hypothalamus; ; hippocampus proper;
	Top expressed in
	superior frontal gyrus; ; supraoptic nucleus; ; ascending aorta; ; ganglionic eminence; ; hippocampus proper; ; cerebellar cortex; ; temporal lobe; ; nucleus accumbens; ; olfactory tubercle; ; ventromedial nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ubiquitin protein ligase activity ; protein binding ;
Cellular component	cytoplasm ; cell cortex ;
Biological process	protein ubiquitination ;
	Sources:Amigo / QuickGO
Orthologs
	57595
	245469
	ENSG00000067840
	ENSMUSG00000002006
	Q76G19 ; Q17RL8
	Q9QY39
NM_032512 ; NM_001303512 ; NM_001303513 ; NM_001303514 ; NM_001303515 ;
	NM_001303516
	NM_001029868 ; NM_001290540
NP_001290441 ; NP_001290442 ; NP_001290443 ; NP_001290444 ; NP_001290445 ;
	NP_115901 ; NP_001290441.1
	NP_001025039 ; NP_001277469
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated September 05, 2022

PDZ domain-containing protein 4 is a protein that in humans is encoded by the PDZD4 gene.^[5]^[6]^[7]

Related Research Articles

Frizzled-2(Fz-2) is a protein that in humans is encoded by the FZD2 gene.

Probable G-protein coupled receptor 45 is a protein that in humans is encoded by the GPR45 gene.

N-acylglucosamine 2-epimerase is an enzyme that in humans is encoded by the RENBP gene.

Sodium- and chloride-dependent creatine transporter 1 is a protein that in humans is encoded by the SLC6A8 gene.

Rho GTPase-activating protein 4 is an enzyme that in humans is encoded by the ARHGAP4 gene. It has been shown to regulate cell motility and axonal outgrowth in vitro.

60S ribosomal protein L36a is a protein that in humans is encoded by the RPL36A gene.

Deoxyribonuclease-1-like 1 is an enzyme that in humans is encoded by the DNASE1L1 gene.

Olfactory receptor 1E2 is a protein that in humans is encoded by the OR1E2 gene.

Phospholemman (PLM) is a protein that in humans is encoded by the FXYD1 gene.

Epithelial membrane protein 1 is a protein that in humans is encoded by the EMP1 gene.

Translocon-associated protein subunit delta is a protein that in humans is encoded by the SSR4 gene.

Homeobox protein DLX-2 is a protein that in humans is encoded by the DLX2 gene.

28S ribosomal protein S22, mitochondrial is a protein that in humans is encoded by the MRPS22 gene.

Protein Wnt-9a is a protein that in humans is encoded by the WNT9A gene.

Protein FAM50A is a protein that in humans is encoded by the FAM50A gene.

PDZ domain-containing RING finger protein 3 is a protein that in humans is encoded by the PDZRN3 gene.

Potassium voltage-gated channel, Shal-related subfamily, member 1 (KCND1), also known as K_v4.1, is a human gene.

Tetraspanin-6 is a protein that in humans is encoded by the TSPAN6 gene.

CAAX box protein 1 is a protein that in humans is encoded by the FAM127A gene.

GIPC PDZ domain containing family, member 2 (GIPC2) is a protein that, in humans, is encoded by the GIPC2 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000067840 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000002006 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (Sep 2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi: 10.1093/dnares/7.2.143 . PMID 10819331.
↑ Nagayama S, Iiizumi M, Katagiri T, Toguchida J, Nakamura Y (Jul 2004). "Identification of PDZK4, a novel human gene with PDZ domains, that is upregulated in synovial sarcomas". Oncogene. 23 (32): 5551–7. doi: 10.1038/sj.onc.1207710 . PMID 15077175.
↑ "Entrez Gene: PDZD4 PDZ domain containing 4".

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Katoh M, Katoh M (2004). "Identification and characterization of human PDZRN4L gene and mouse Pdzrn4l gene in silico". Int. J. Mol. Med. 13 (6): 923–7. doi:10.3892/ijmm.13.6.923. PMID 15138636.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Brenner V, Nyakatura G, Rosenthal A, Platzer M (1997). "Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse". Genomics. 44 (1): 8–14. doi:10.1006/geno.1997.4822. PMID 9286695.
Sandoval N, Bauer D, Brenner V, et al. (1996). "The genomic organization of a human creatine transporter (CRTR) gene located in Xq28". Genomics. 35 (2): 383–5. doi:10.1006/geno.1996.0373. PMID 8661155.

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000067840 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000002006 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10819331-5] Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (Sep 2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi: 10.1093/dnares/7.2.143 . PMID 10819331.

[pmid15077175-6] Nagayama S, Iiizumi M, Katagiri T, Toguchida J, Nakamura Y (Jul 2004). "Identification of PDZK4, a novel human gene with PDZ domains, that is upregulated in synovial sarcomas". Oncogene. 23 (32): 5551–7. doi: 10.1038/sj.onc.1207710 . PMID 15077175.

[entrez-7] "Entrez Gene: PDZD4 PDZ domain containing 4".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

PDZD4

Related Research Articles

References

Further reading