PGK1

PGK1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2WZB, 2WZC, 2WZD, 2X13, 2X14, 2X15, 2XE6, 2XE7, 2XE8, 2Y3I, 2YBE, 2ZGV, 3C39, 3C3A, 3C3B, 3C3C, 3ZOZ, 4AXX, 4O33 Contents Interactive pathway map ; References ; Further reading ; External links ;
Identifiers
Aliases	PGK1 , HEL-S-68p, MIG10, PGKA, phosphoglycerate kinase 1
External IDs	OMIM: 311800; MGI: 97555; HomoloGene: 21542; GeneCards: PGK1; OMA:PGK1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	78,129,295 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	105,247,305 bp
RNA expression pattern
	Top expressed in
	tibia; ; germinal epithelium; ; right ventricle; ; pericardium; ; parotid gland; ; Skeletal muscle tissue of rectus abdominis; ; pons; ; lateral nuclear group of thalamus; ; trabecular bone; ; palpebral conjunctiva;
	Top expressed in
	quadriceps femoris muscle; ; epiblast; ; muscle of thigh; ; skeletal muscle tissue; ; neural layer of retina; ; tail of embryo; ; granulocyte; ; ventricular zone; ; embryo; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity ; nucleotide binding ; protein binding ; ATP binding ; kinase activity ; phosphoglycerate kinase activity ; protein-disulfide reductase (NAD(P)) activity ; ADP binding ;
Cellular component	cytoplasm ; membrane raft ; cytosol ; extracellular exosome ; membrane ; extracellular space ;
Biological process	gluconeogenesis ; epithelial cell differentiation ; phosphorylation ; canonical glycolysis ; glycolytic process ; negative regulation of angiogenesis ; plasminogen activation ; cellular response to hypoxia ; response to hypoxia ; chemical synaptic transmission ; myoblast fusion ; somatic muscle development ; muscle cell cellular homeostasis ; positive regulation of oxidative phosphorylation ;
	Sources:Amigo / QuickGO
Orthologs
	5230
	18655
	ENSG00000102144
	ENSMUSG00000062070
	P00558
	P09411
	NM_000291
	NM_008828
	NP_000282
	NP_032854
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated November 03, 2024

Phosphoglycerate kinase 1 is an enzyme that in humans is encoded by the PGK1 gene.^[5]^[6]^[7]

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles.^{[§ 1]}

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|alt=Glycolysis and Gluconeogenesis edit]]

Glycolysis and Gluconeogenesis edit

↑ The interactive pathway map can be edited at WikiPathways: "GlycolysisGluconeogenesis_WP534".

Related Research Articles

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Phosphoglycerate kinase is an enzyme that catalyzes the reversible transfer of a phosphate group from 1,3-bisphosphoglycerate (1,3-BPG) to ADP producing 3-phosphoglycerate (3-PG) and ATP :

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000102144 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000062070 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Michelson AM, Markham AF, Orkin SH (May 1983). "Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase". Proc Natl Acad Sci U S A. 80 (2): 472–6. Bibcode:1983PNAS...80..472M. doi: 10.1073/pnas.80.2.472 . PMC 393400 . PMID 6188151.
↑ Singer-Sam J, Keith DH, Tani K, Simmer RL, Shively L, Lindsay S, Yoshida A, Riggs AD (May 1985). "Sequence of the promoter region of the gene for human X-linked 3-phosphoglycerate kinase]". Gene. 32 (3): 409–17. doi:10.1016/0378-1119(84)90016-7. PMID 6099325.
↑ "Entrez Gene: PGK1 phosphoglycerate kinase 1".

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Phosphoglycerate kinase 1

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
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[WikiPathways-8] The interactive pathway map can be edited at WikiPathways: "GlycolysisGluconeogenesis_WP534".

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000102144 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000062070 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid6188151-5] Michelson AM, Markham AF, Orkin SH (May 1983). "Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase". Proc Natl Acad Sci U S A. 80 (2): 472–6. Bibcode:1983PNAS...80..472M. doi: 10.1073/pnas.80.2.472 . PMC 393400 . PMID 6188151.

[pmid6099325-6] Singer-Sam J, Keith DH, Tani K, Simmer RL, Shively L, Lindsay S, Yoshida A, Riggs AD (May 1985). "Sequence of the promoter region of the gene for human X-linked 3-phosphoglycerate kinase]". Gene. 32 (3): 409–17. doi:10.1016/0378-1119(84)90016-7. PMID 6099325.

[7] "Entrez Gene: PGK1 phosphoglycerate kinase 1".

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[§ 1]

PGK1

Contents

Interactive pathway map

Related Research Articles

References

Further reading

External links