PIGW

Last updated
PIGW
Identifiers
Aliases PIGW , Gwt1, HPMRS5, phosphatidylinositol glycan anchor biosynthesis class W
External IDs OMIM: 610275 MGI: 1917575 HomoloGene: 6243 GeneCards: PIGW
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_178517
NM_001346754
NM_001346755

NM_001077636
NM_027388
NM_001363112

RefSeq (protein)

NP_001333683
NP_001333684
NP_848612

NP_001071104
NP_081664
NP_001350041

Location (UCSC) Chr 17: 36.53 – 36.54 Mb Chr 11: 84.77 – 84.77 Mb
PubMed search [3] [4]
Wikidata
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Phosphatidylinositol glycan anchor biosynthesis class W is a protein that in humans is encoded by the PIGW gene. [5]

Contents

Function

Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003 [PubMed 14517336]).

Related Research Articles

<span class="mw-page-title-main">Phosphatidylinositol transfer protein, alpha</span> Protein-coding gene in the species Homo sapiens

Phosphatidylinositol transfer protein alpha isoform is a protein that in humans is encoded by the PITPNA gene.

<span class="mw-page-title-main">PIGA</span> Protein-coding gene in the species Homo sapiens

Phosphatidylinositol N-acetylglucosaminyltransferase subunit A is the catalytic subunit of the phosphatidylinositol N-acetylglucosaminyltransferase enzyme, which in humans is encoded by the PIGA gene.

<span class="mw-page-title-main">GPLD1</span>

Phosphatidylinositol-glycan-specific phospholipase D is an enzyme that in humans is encoded by the GPLD1 gene.

<span class="mw-page-title-main">PIGT</span>

GPI transamidase component PIG-T is an enzyme that in humans is encoded by the PIGT gene.

<span class="mw-page-title-main">PIGK</span> Protein-coding gene in the species Homo sapiens

GPI-anchor transamidase is an enzyme that in humans is encoded by the PIGK gene.

<span class="mw-page-title-main">PIGQ</span>

Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q is an enzyme that in humans is encoded by the PIGQ gene.

<span class="mw-page-title-main">PIGC</span> Enzyme

Phosphatidylinositol N-acetylglucosaminyltransferase subunit C is an enzyme that in humans is encoded by the PIGC gene.

<span class="mw-page-title-main">PIGF</span>

Phosphatidylinositol-glycan biosynthesis class F protein is a protein that in humans is encoded by the PIGF gene.

<span class="mw-page-title-main">PITPNB</span>

Phosphatidylinositol transfer protein beta isoform is a protein that in humans is encoded by the PITPNB gene.

<span class="mw-page-title-main">PIGS (gene)</span> Protein-coding gene in the species Homo sapiens

GPI transamidase component PIG-S is an enzyme that in humans is encoded by the PIGS gene. This gene encodes a protein that is involved in GPI-anchor biosynthesis.

<span class="mw-page-title-main">PIGU</span>

Phosphatidylinositol glycan anchor biosynthesis class U protein is a protein that in humans is encoded by the PIGU gene.

<span class="mw-page-title-main">PIGB</span>

GPI mannosyltransferase 3 is an enzyme that in humans is encoded by the PIGB gene.

<span class="mw-page-title-main">Placental alkaline phosphatase</span> Protein-coding gene in the species Homo sapiens

Alkaline phosphatase, placental type also known as placental alkaline phosphatase (PLAP) is an allosteric enzyme that in humans is encoded by the ALPP gene.

<span class="mw-page-title-main">PIGP</span> Protein-coding gene in the species Homo sapiens

Subunit P of phosphatidylinositol N-acetylglucosaminyltransferase is an enzyme that in humans is encoded by the PIGP gene.

<span class="mw-page-title-main">PIGH</span>

Phosphatidylinositol N-acetylglucosaminyltransferase subunit H is an enzyme that in humans is encoded by the PIGH gene. The PIGH gene is located on the reverse strand of chromosome 14 in humans, and is neighbored by TMEM229B.

<span class="mw-page-title-main">PIGV</span> Protein-coding gene in the species Homo sapiens

GPI mannosyltransferase 2 is an enzyme that in humans is encoded by the PIGV gene.

<span class="mw-page-title-main">TMEM229B</span> Gene of the species Homo sapiens

Transmembrane protein 229b is a protein that in humans is encoded by the TMEM229b gene.

<span class="mw-page-title-main">PIGN (gene)</span>

Phosphatidylinositol glycan anchor biosynthesis, class N is a protein that in humans is encoded by the PIGN gene.

<span class="mw-page-title-main">PGAP1</span>

Post-GPI attachment to proteins 1 is a protein that in humans is encoded by the PGAP1 gene.

<span class="mw-page-title-main">MTMR12</span>

Myotubularin related protein 12 is a protein that in humans is encoded by the MTMR12 gene.

References

  1. 1 2 3 ENSG00000277161 GRCh38: Ensembl release 89: ENSG00000275600, ENSG00000277161 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000045140 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Phosphatidylinositol glycan anchor biosynthesis class W" . Retrieved 2016-10-29.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.