PITPNB

PITPNB
Identifiers
Aliases	PITPNB , PI-TP-beta, PtdInsTP, VIB1B, phosphatidylinositol transfer protein beta
External IDs	OMIM: 606876 MGI: 1927542 HomoloGene: 4533 GeneCards: PITPNB
Gene location (Human)
Chr.	Chromosome 22 (human)
End	27,920,134 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	111,536,225 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; endothelial cell; ; middle temporal gyrus; ; germinal epithelium; ; Brodmann area 23; ; superficial temporal artery; ; hair follicle; ; parietal pleura; ; Brodmann area 46; ; popliteal artery;
	Top expressed in
	condyle; ; fossa; ; ciliary body; ; hair follicle; ; retinal pigment epithelium; ; conjunctival fornix; ; internal carotid artery; ; iris; ; Paneth cell; ; external carotid artery;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	lipid binding ; phosphatidylcholine transporter activity ; phosphatidylinositol transfer activity ; phosphatidylcholine binding ; phosphatidylinositol binding ; phospholipid transporter activity ;
Cellular component	cytoplasm ; Golgi membrane ; Golgi apparatus ; endoplasmic reticulum membrane ; intracellular anatomical structure ;
Biological process	lipid metabolism ; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum ; nucleus organization ; phospholipid transport ;
	Sources:Amigo / QuickGO
Orthologs
	23760
	56305
	ENSG00000180957
	ENSMUSG00000050017
	P48739
	P53811
	NM_001284277 ; NM_001284278 ; NM_012399
NM_001301643 ; NM_001301644 ; NM_001301666 ; NM_019640 ; NM_001359215 ;
	NM_001359216 ; NM_001359217
	NP_001271206 ; NP_001271207 ; NP_036531
NP_001288572 ; NP_001288573 ; NP_001288595 ; NP_062614 ; NP_001346144 ;
	NP_001346145 ; NP_001346146
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 05, 2023

Phosphatidylinositol transfer protein beta isoform is a protein that in humans is encoded by the PITPNB gene.^[5]^[6]

The protein encoded by this gene is found in the cytoplasm, where it catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes.^[6]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000180957 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000050017 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al. (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi: 10.1038/990031 . PMID 10591208.
1 2 "Entrez Gene: PITPNB phosphatidylinositol transfer protein, beta".

PITPNB

Related Research Articles

References

Further reading