PLEKHF2

PLEKHF2
Identifiers
Aliases	PLEKHF2 , EAPF, PHAFIN2, ZFYVE18, pleckstrin homology and FYVE domain containing 2
External IDs	OMIM: 615208; MGI: 1919051; HomoloGene: 11620; GeneCards: PLEKHF2; OMA:PLEKHF2 - orthologs
Gene location (Human) Chr. Chromosome 8 (human) [1] Band 8q22.1 Start 95,133,785 bp [1] End 95,156,685 bp [1]
Gene location (Mouse) Chr. Chromosome 4 (mouse) [2] Band 4|4 A1 Start 10,988,662 bp [2] End 11,007,927 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte skin of thigh palpebral conjunctiva bronchial epithelial cell skin of hip monocyte sperm bone marrow corpus epididymis olfactory zone of nasal mucosa Top expressed in granulocyte right kidney neural layer of retina yolk sac spermatocyte morula proximal tubule endocardial cushion lip atrioventricular valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding phosphatidylinositol binding Cellular component endosome early endosome membrane transport vesicle endoplasmic reticulum membrane Biological process protein transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79666 71801 Ensembl ENSG00000175895 ENSMUSG00000049969 UniProt Q9H8W4 Q91WB4 RefSeq (mRNA) NM_024613 NM_175175 RefSeq (protein) NP_078889 NP_780384 Location (UCSC) Chr 8: 95.13 – 95.16 Mb Chr 4: 10.99 – 11.01 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Pleckstrin homology domain-containing family F member 2 is a protein that in humans is encoded by the PLEKHF2 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000175895 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000049969 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.