POP7 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | POP7 , 0610037N12Rik, RPP2, RPP20, POP7 homolog, ribonuclease P/MRP subunit | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 606113 MGI: 1921347 HomoloGene: 4262 GeneCards: POP7 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Ribonuclease P protein subunit p20 is an enzyme that in humans is encoded by the POP7 gene. [5] [6]
Angiogenin (ANG) also known as ribonuclease 5 is a small 123 amino acid protein that in humans is encoded by the ANG gene. Angiogenin is a potent stimulator of new blood vessels through the process of angiogenesis. Ang hydrolyzes cellular RNA, resulting in modulated levels of protein synthesis and interacts with DNA causing a promoter-like increase in the expression of rRNA. Ang is associated with cancer and neurological disease through angiogenesis and through activating gene expression that suppresses apoptosis.
Ribonuclease P is a type of ribonuclease which cleaves RNA. RNase P is unique from other RNases in that it is a ribozyme – a ribonucleic acid that acts as a catalyst in the same way that a protein-based enzyme would. Its function is to cleave off an extra, or precursor, sequence of RNA on tRNA molecules. Further, RNase P is one of two known multiple turnover ribozymes in nature, the discovery of which earned Sidney Altman and Thomas Cech the Nobel Prize in Chemistry in 1989: in the 1970s, Altman discovered the existence of precursor tRNA with flanking sequences and was the first to characterize RNase P and its activity in processing of the 5' leader sequence of precursor tRNA. Recent findings also reveal that RNase P has a new function. It has been shown that human nuclear RNase P is required for the normal and efficient transcription of various small noncoding RNAs, such as tRNA, 5S rRNA, SRP RNA and U6 snRNA genes, which are transcribed by RNA polymerase III, one of three major nuclear RNA polymerases in human cells.
Eosinophil-derived neurotoxin is an enzyme that in humans is encoded by the RNASE2 gene.
Splicing factor 3 subunit 1 is a protein that in humans is encoded by the SF3A1 gene.
RNA polymerase II subunit A C-terminal domain phosphatase is an enzyme that in humans is encoded by the CTDP1 gene.
Ribonucleases P/MRP protein subunit POP1 is a protein that in humans is encoded by the POP1 gene.
Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex.
Ribonuclease P/MRP protein subunit POP5 is an enzyme that in humans is encoded by the POP5 gene.
Poly(A) polymerase alpha is an enzyme that in humans is encoded by the PAPOLA gene.
Cleavage stimulation factor 77 kDa subunit is a protein that in humans is encoded by the CSTF3 gene.
Ribonuclease P protein subunit p30 is an enzyme that in humans is encoded by the RPP30 gene.
Ribonuclease P protein subunit p38 is an enzyme that in humans is encoded by the RPP38 gene.
Ribonuclease P protein subunit p14 is an enzyme that in humans is encoded by the RPP14 gene.
40S ribosomal protein S15 is a protein that in humans is encoded by the RPS15 gene.
Anaphase-promoting complex subunit 4 is an enzyme that in humans is encoded by the ANAPC4 gene.
28S ribosomal protein S24, mitochondrial is a protein that in humans is encoded by the MRPS24 gene.
Nucleolar protein 6 is a protein that in humans is encoded by the NOL6 gene.
RRP15-like protein is a protein that in humans is encoded by the RRP15 gene.
39S ribosomal protein L17, mitochondrial is a protein that in humans is encoded by the MRPL17 gene.
Ribonuclease H2 subunit A, also known as RNase H2 subunit A, is an enzyme that in humans is encoded by the RNASEH2A gene.