PPP1R14C

PPP1R14C
Identifiers
Aliases	PPP1R14C , CPI17-like, KEPI, NY-BR-81, protein phosphatase 1 regulatory inhibitor subunit 14C
External IDs	OMIM: 613242; MGI: 1923392; HomoloGene: 12805; GeneCards: PPP1R14C; OMA:PPP1R14C - orthologs
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6q25.1 Start 150,143,044 bp [1] End 150,250,392 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 A1 Start 3,316,057 bp [2] End 3,414,975 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of arm cardiac muscle tissue of right atrium myocardium of left ventricle secondary oocyte cartilage tissue bronchial epithelial cell Skeletal muscle tissue of rectus abdominis skin of thigh skin of abdomen skin of hip Top expressed in interventricular septum left ventricle quadriceps femoris muscle muscle tissue skeletal muscle tissue muscle of thigh lung zone of skin lip ganglionic eminence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein phosphatase inhibitor activity protein serine/threonine phosphatase inhibitor activity Cellular component cytoplasm membrane Biological process regulation of phosphorylation negative regulation of phosphoprotein phosphatase activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81706 76142 Ensembl ENSG00000198729 ENSMUSG00000040653 UniProt Q8TAE6 Q8R4S0 RefSeq (mRNA) NM_030949 NM_133485 RefSeq (protein) NP_112211 NP_597844 Location (UCSC) Chr 6: 150.14 – 150.25 Mb Chr 10: 3.32 – 3.41 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protein phosphatase 1 regulatory subunit 14C is an enzyme that in humans is encoded by the PPP1R14C gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000198729 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000040653 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ceulemans H, Stalmans W, Bollen M (Apr 2002). "Regulator-driven functional diversification of protein phosphatase-1 in eukaryotic evolution". BioEssays. 24 (4): 371–81. doi:10.1002/bies.10069. PMID   11948623.
6. "Entrez Gene: PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C".

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID   14574404.
• Scanlan MJ, Gout I, Gordon CM, et al. (2003). "Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression". Cancer Immun. 1: 4. PMID   12747765.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Liu QR, Zhang PW, Zhen Q, et al. (2002). "KEPI, a PKC-dependent protein phosphatase 1 inhibitor regulated by morphine". J. Biol. Chem. 277 (15): 13312–20. doi: 10.1074/jbc.M107558200 . PMID   11812771.
• Connor JH, Weiser DC, Li S, et al. (2001). "Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1". Mol. Cell. Biol. 21 (20): 6841–50. doi:10.1128/MCB.21.20.6841-6850.2001. PMC   99861 . PMID   11564868.