PPP2R3C

PPP2R3C
Identifiers
Aliases	PPP2R3C , C14orf10, G4-1, G5pr, SPGF36, GDRM, protein phosphatase 2 regulatory subunit B''gamma
External IDs	OMIM: 615902 MGI: 1930009 HomoloGene: 9915 GeneCards: PPP2R3C
Gene location (Mouse) Chr. Chromosome 12 (mouse) [1] Band 12|12 C1 Start 55,278,991 bp [1] End 55,302,998 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence monocyte sperm blood Achilles tendon anterior pituitary bone marrow spleen amygdala prefrontal cortex Top expressed in spermatocyte spermatid morula superior frontal gyrus yolk sac neural tube ascending aorta ganglionic eminence proximal tubule aortic valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding Cellular component cytoplasm centrosome spindle nucleus Golgi apparatus cytosol Biological process positive regulation of B cell differentiation regulation of B cell activation cortical cytoskeleton organization B cell homeostasis spleen development activation of protein kinase activity microtubule cytoskeleton organization regulation of mitochondrial depolarization regulation of antimicrobial humoral response T cell homeostasis regulation of dephosphorylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55012 59032 Ensembl n/a ENSMUSG00000021022 UniProt Q969Q6 Q9JK24 RefSeq (mRNA) NM_001305155 NM_001305156 NM_017917 NM_021529 RefSeq (protein) NP_001292084 NP_001292085 NP_060387 NP_067504 Location (UCSC) n/a Chr 12: 55.28 – 55.3 Mb PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma is an enzyme that in humans is encoded by the PPP2R3C gene. ^{[4] [5] [6]}

References

1. GRCm38: Ensembl release 89: ENSMUSG00000021022 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Kono Y, Maeda K, Kuwahara K, Yamamoto H, Miyamoto E, Yonezawa K, Takagi K, Sakaguchi N (Aug 2002). "MCM3-binding GANP DNA-primase is associated with a novel phosphatase component G5PR". Genes Cells. 7 (8): 821–34. doi:10.1046/j.1365-2443.2002.00562.x. PMID   12167160. S2CID   21946802.
5. Xing Y, Igarashi H, Wang X, Sakaguchi N (Sep 2005). "Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor–induced apoptosis". J Exp Med. 202 (5): 707–19. doi:10.1084/jem.20050637. PMC   2212881 . PMID   16129705.
6. "Entrez Gene: PPP2R3C protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma".

Further reading

• Kamnasaran D, Chen CP, Devriendt K, et al. (2005). "Defining a holoprosencephaly locus on human chromosome 14q13 and characterization of potential candidate genes". Genomics. 85 (5): 608–21. doi:10.1016/j.ygeno.2005.01.010. PMID   15820313.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.