PRPF40B

PRPF40B
Identifiers
Aliases	PRPF40B , HYPC, pre-mRNA processing factor 40 homolog B
External IDs	MGI: 1925583; HomoloGene: 81828; GeneCards: PRPF40B; OMA:PRPF40B - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q13.12 Start 49,568,218 bp [1] End 49,644,666 bp [1]
Gene location (Mouse) Chr. Chromosome 15 (mouse) [2] Band 15|15 F1 Start 99,295,087 bp [2] End 99,317,018 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of thyroid gland left lobe of thyroid gland anterior pituitary left testis sural nerve right testis left ovary right uterine tube right ovary canal of the cervix Top expressed in neural layer of retina primary visual cortex ventricular zone superior frontal gyrus genital tubercle tail of embryo dentate gyrus of hippocampal formation granule cell spermatocyte muscle of thigh cerebellar cortex More reference expression data BioGPS n/a
Gene ontology Molecular function RNA binding Cellular component U1 snRNP nuclear speck U2-type prespliceosome nucleus Biological process mRNA splicing, via spliceosome mRNA processing RNA splicing mRNA cis splicing, via spliceosome Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25766 54614 Ensembl ENSG00000110844 ENSMUSG00000023007 UniProt Q6NWY9 Q80W14 RefSeq (mRNA) NM_001031698 NM_012272 NM_001363607 NM_001379030 NM_001379031 NM_001379032 NM_001379033 NM_001379034 NM_001379035 NM_001379036 NM_001379037 NM_018786 NM_001348256 RefSeq (protein) NP_001026868 NP_036404 NP_001350536 NP_001365959 NP_001365960 NP_001365961 NP_001365962 NP_001365963 NP_001365964 NP_001365965 NP_001365966 NP_061256 NP_001335185 NP_001357561 NP_001357562 NP_001357563 NP_001357564 Location (UCSC) Chr 12: 49.57 – 49.64 Mb Chr 15: 99.3 – 99.32 Mb PubMed search [3] [4]
Wikidata
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Pre-mRNA-processing factor 40 homolog B is a protein that in humans that is encoded by the PRPF40B gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000110844 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000023007 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)" . Retrieved 2012-04-15.

Further reading

• Buschdorf JP, Strätling WH (Feb 2004). "A WW domain binding region in methyl-CpG-binding protein MeCP2: impact on Rett syndrome". Journal of Molecular Medicine. 82 (2): 135–43. doi:10.1007/s00109-003-0497-9. PMID   14618241. S2CID   9685491.
• Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics. 7 (9): 1463–74. doi: 10.1093/hmg/7.9.1463 . PMID   9700202.