PRPSAP2

Last updated
PRPSAP2
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PRPSAP2 , PAP41, phosphoribosyl pyrophosphate synthetase associated protein 2
External IDs OMIM: 603762; MGI: 2384838; HomoloGene: 2073; GeneCards: PRPSAP2; OMA:PRPSAP2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC) Chr 17: 18.84 – 18.93 Mb Chr 11: 61.62 – 61.65 Mb
PubMed search [3] [4]
Wikidata
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Phosphoribosyl pyrophosphate synthetase-associated protein 2 is a protein that in humans is encoded by the PRPSAP2 gene. [5]

Function

The enzyme phosphoribosyl pyrophosphate synthetase (PRS) catalyzes the formation of phosphoribosyl pyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. [5]

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000141127 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020528 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: phosphoribosyl pyrophosphate synthetase-associated protein 2" . Retrieved 2011-08-30.

Further reading