PSG6

Last updated
PSG6
Identifiers
Aliases PSG6 , PSBG-10, PSBG-12, PSBG-6, PSG10, PSGGB, pregnancy specific beta-1-glycoprotein 6
External IDs OMIM: 176395 HomoloGene: 136760 GeneCards: PSG6
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002782
NM_001031850

n/a

RefSeq (protein)

NP_001027020
NP_002773

n/a

Location (UCSC) Chr 19: 42.9 – 42.92 Mb n/a
PubMed search [2] n/a
Wikidata
View/Edit Human

Pregnancy-specific beta-1-glycoprotein 6 is a protein that in humans is encoded by the PSG6 gene. [3] [4]

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Pregnancy specific beta-1-glycoprotein 1 (PSBG-1) also known as CD66f, is a protein that in humans is encoded by the PSG1 gene and is a member of the carcinoembryonic antigen (CEA) gene family. Pregnancy-specific glycoproteins (PSGs) are a complex consisting of carbohydrate and protein, which is present in the mammalian body specifically during pregnancy. This glycoprotein is the most abundant protein found in the maternal bloodstream during the later stages of pregnancy and it is of vital importance in fetal development. The PSG functions primarily as an immunomodulator to protect the growing fetus.

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000170848 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Thompson J, Koumari R, Wagner K, Barnert S, Schleussner C, Schrewe H, Zimmermann W, Muller G, Schempp W, Zaninetta D, et al. (May 1990). "The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed". Biochem Biophys Res Commun. 167 (2): 848–59. CiteSeerX   10.1.1.655.1870 . doi:10.1016/0006-291X(90)92103-7. PMID   1690992.
  4. "Entrez Gene: PSG6 pregnancy specific beta-1-glycoprotein 6".

Further reading