PTGES3

Last updated

PTGES3
Protein PTGES3 PDB 1ejf.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PTGES3 , P23, TEBP, cPGES, prostaglandin E synthase 3
External IDs OMIM: 607061; MGI: 1929282; HomoloGene: 128197; GeneCards: PTGES3; OMA:PTGES3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_019766

RefSeq (protein)

NP_062740

Location (UCSC) Chr 12: 56.66 – 56.69 Mb Chr 10: 127.89 – 127.91 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Prostaglandin E synthase 3 (cytosolic) is a Prostaglandin E synthase enzyme that in humans is encoded by the PTGES3 gene. [5]

The protein encoded by this gene is also known as p23 which functions as a chaperone which is required for proper functioning of the glucocorticoid and other steroid receptors. [6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000110958 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000071072 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: PTGES3 Prostaglandin E synthase 3 (cytosolic)".
  6. Freeman BC, Yamamoto KR (June 2002). "Disassembly of transcriptional regulatory complexes by molecular chaperones". Science. 296 (5576): 2232–2235. Bibcode:2002Sci...296.2232F. doi:10.1126/science.1073051. PMID   12077419. S2CID   8844179.

Further reading