PWP1

PWP1
Identifiers
Aliases	PWP1 , IEF-SSP-9502, PWP1 homolog, endonuclein
External IDs	MGI: 1914735 HomoloGene: 5129 GeneCards: PWP1
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	85,724,960 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; nipple; ; pylorus; ; cardia; ; renal medulla; ; pericardium; ; Achilles tendon; ; vulva; ; pons; ; parietal pleura;
	Top expressed in
	primitive streak; ; abdominal wall; ; Paneth cell; ; spermatocyte; ; medial ganglionic eminence; ; morula; ; hair follicle; ; maxillary prominence; ; vas deferens; ; motor neuron;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	H4K20me3 modified histone binding ;
Cellular component	nucleus ; Golgi apparatus ; nucleolus ; chromosome ;
Biological process	transcription, DNA-templated ; positive regulation of stem cell differentiation ; histone H4-K20 trimethylation ; negative regulation of peptidyl-serine phosphorylation of STAT protein ; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I ; ribosome biogenesis ;
	Sources:Amigo / QuickGO
Orthologs
	11137
	103136
	n/a
	ENSMUSG00000001785
	Q13610
	Q99LL5
	NM_007062 ; NM_001317962 ; NM_001317963
	NM_133993
	NP_001304891 ; NP_001304892 ; NP_008993
	NP_598754
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated April 11, 2024

Periodic tryptophan protein 1 homolog is a protein that in humans is encoded by the PWP1 gene.^[4]^[5]

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References

1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001785 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Honore B, Leffers H, Madsen P, Celis JE (Feb 1995). "Cloning of a cDNA encoding a novel human nuclear phosphoprotein belonging to the WD-40 family". Gene. 151 (1–2): 291–6. doi:10.1016/0378-1119(94)90673-4. PMID 7828893.
↑ "Entrez Gene: PWP1 PWP1 homolog (S. cerevisiae)".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Gress TM, Müller-Pillasch F, Geng M, et al. (1996). "A pancreatic cancer-specific expression profile". Oncogene. 13 (8): 1819–30. PMID 8895530.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi: 10.1016/S0960-9822(01)00650-9 . PMID 11790298. S2CID 14132033.
Honoré B, Baandrup U, Nielsen S, Vorum H (2002). "Endonuclein is a cell cycle regulated WD-repeat protein that is up-regulated in adenocarcinoma of the pancreas". Oncogene. 21 (7): 1123–9. doi:10.1038/sj.onc.1205186. PMID 11850830. S2CID 1657629.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC 514446 . PMID 15302935.
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi: 10.1073/pnas.0507066103 . PMC 1459365 . PMID 16565220.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID 17081983. S2CID 7827573.

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[refGRCm38Ensembl-1] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001785 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7828893-4] Honore B, Leffers H, Madsen P, Celis JE (Feb 1995). "Cloning of a cDNA encoding a novel human nuclear phosphoprotein belonging to the WD-40 family". Gene. 151 (1–2): 291–6. doi:10.1016/0378-1119(94)90673-4. PMID 7828893.

[entrez-5] "Entrez Gene: PWP1 PWP1 homolog (S. cerevisiae)".

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[3]

[4]

[5]

PWP1

Related Research Articles

References

Further reading