PXMP4

PXMP4
Identifiers
Aliases	PXMP4 , PMP24, peroxisomal membrane protein 4
External IDs	OMIM: 616397; MGI: 1891701; HomoloGene: 5237; GeneCards: PXMP4; OMA:PXMP4 - orthologs
Gene location (Human) Chr. Chromosome 20 (human) [1] Band 20q11.22 Start 33,702,758 bp [1] End 33,720,319 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 H1 Start 154,427,678 bp [2] End 154,445,628 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of thigh right adrenal cortex pancreatic ductal cell vulva left adrenal gland left adrenal cortex muscle of thigh parotid gland mucosa of ileum mucosa of transverse colon Top expressed in right kidney lip left lobe of liver proximal tubule human kidney right ventricle embryo brown adipose tissue muscle of thigh skin of external ear More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component integral component of membrane peroxisomal membrane peroxisome membrane Biological process biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11264 59038 Ensembl ENSG00000101417 ENSMUSG00000000876 UniProt Q9Y6I8 Q9JJW0 RefSeq (mRNA) NM_183397 NM_007238 NM_021534 RefSeq (protein) NP_009169 NP_899634 NP_067509 Location (UCSC) Chr 20: 33.7 – 33.72 Mb Chr 2: 154.43 – 154.45 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Peroxisomal membrane protein 4 is a protein that in humans is encoded by the PXMP4 gene. ^{[5] [6]} PXMP4 is also known as 24kDa peroxisomal intrinsic membrane protein. ^[7]

References

1. GRCh38: Ensembl release 89: ENSG00000101417 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000000876 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Reguenga C, Oliveira ME, Gouveia AM, Eckerskorn C, Sa-Miranda C, Azevedo JE (Jul 1999). "Identification of a 24 kDa intrinsic membrane protein from mammalian peroxisomes". Biochim Biophys Acta. 1445 (3): 337–41. doi:10.1016/s0167-4781(99)00061-5. PMID   10366717.
6. "Entrez Gene: PXMP4 peroxisomal membrane protein 4, 24kDa".
7. "UniProt". www.uniprot.org. Retrieved 2024-10-21.

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Jones JM, Morrell JC, Gould SJ (2004). "PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins". J. Cell Biol. 164 (1): 57–67. doi:10.1083/jcb.200304111. PMC   2171958 . PMID   14709540.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi: 10.1038/414865a . PMID   11780052.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Sacksteder KA, Jones JM, South ST, et al. (2000). "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis". J. Cell Biol. 148 (5): 931–44. doi:10.1083/jcb.148.5.931. PMC   2174547 . PMID   10704444.