Related Research Articles
Mycobacterium is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis and leprosy in humans. The Greek prefix myco- means 'fungus', alluding to this genus' mold-like colony surfaces. Since this genus has cell walls with Gram-positive and Gram-negative features, acid-fast staining is used to emphasize their resistance to acids, compared to other cell types.
In cell biology, a phagosome is a vesicle formed around a particle engulfed by a phagocyte via phagocytosis. Professional phagocytes include macrophages, neutrophils, and dendritic cells (DCs).
In biochemistry, an orphan receptor is a protein that has a similar structure to other identified receptors but whose endogenous ligand has not yet been identified. If a ligand for an orphan receptor is later discovered, the receptor is referred to as an "adopted orphan". Conversely, the term orphan ligand refers to a biological ligand whose cognate receptor has not yet been identified.
In the field of molecular biology, the pregnane X receptor (PXR), also known as the steroid and xenobiotic sensing nuclear receptor (SXR) or nuclear receptor subfamily 1, group I, member 2 (NR1I2) is a protein that in humans is encoded by the NR1I2 gene.
The constitutive androstane receptor (CAR) also known as nuclear receptor subfamily 1, group I, member 3 is a protein that in humans is encoded by the NR1I3 gene. CAR is a member of the nuclear receptor superfamily and along with pregnane X receptor (PXR) functions as a sensor of endobiotic and xenobiotic substances. In response, expression of proteins responsible for the metabolism and excretion of these substances is upregulated. Hence, CAR and PXR play a major role in the detoxification of foreign substances such as drugs.
Interleukin 27 (IL-27) is a member of the IL-12 cytokine family. It is a heterodimeric cytokine that is encoded by two distinct genes, Epstein-Barr virus-induced gene 3 (EBI3) and IL-27p28. IL-27 is expressed by antigen presenting cells and interacts with a specific cell-surface receptor complex known as IL-27 receptor (IL-27R). This receptor consists of two proteins, IL-27Rɑ and gp130. IL-27 induces differentiation of the diverse populations of T cells in the immune system and also upregulates IL-10.
Liver X receptor alpha (LXR-alpha) is a nuclear receptor protein that in humans is encoded by the NR1H3 gene.
Ssshhhh... Koi Hai is an Indian horror thriller television anthology series created by Cinevistaas Limited and Contiloe Entertainment for Star Plus. The first season was created by them together, while later seasons were only created by Abhimanyu Raj Singh and were aired on Star Plus' sister channel Star One. The series which premiered on 27 July 2001, ran for three seasons ending on 16 May 2010.
Niyaz Ahmed is a molecular epidemiologist, professor of microbial sciences, genomicist, and a veterinarian by training, based in Hyderabad.
Kanury Raoalso known as Kanury Venkata Subba Rao is an Indian immunologist. He was the head of the Drug Discovery Research Centre (DDRC) at the Translational Health Science and Technology Institute (THSTI) Faridabad..He is known for his studies in the fields of peptide synthesis and cell signaling and the design of synthetic peptide vaccines. He is an elected fellow of the Indian Academy of Sciences, National Academy of Sciences, India and the Indian National Science Academy. and a recipient of several awards including the Millennium Plaque of Honour of the Indian Science Congress and the National Bioscience Award for Career Development. The Council of Scientific and Industrial Research awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, in 1997, for his contributions to biological sciences.
Vinod Bhakuni (1962–2011) was an Indian molecular biophysicist and the head of the Molecular and Structural Biology Division of the Central Drug Research Institute (CDRI). He was the founder of the Protein Chemistry laboratory of CDRI and was known for his contributions to the study of protein folding. A recipient of the National Bioscience Award for Career Development, he was an elected fellow of the Indian Academy of Sciences, Indian National Science Academy and the National Academy of Sciences, India. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2006, for his contributions to biological sciences.
Joyoti Basu is an Indian biochemist, cell biologist and a senior professor at the Bose Institute. Known for her studies on the membrane structure of red blood cells, Basu is an elected fellow of all three major Indian science academies, namely the National Academy of Sciences, India, the Indian Academy of Sciences and the Indian National Science Academy, as well as the Indian Society for Chemical Biology. The Department of Biotechnology of the Government of India awarded her the National Bioscience Award for Career Development, one of the highest Indian science awards, for her contributions to biosciences in 2002.
Sangita Mukhopadhyay is an Indian molecular cell biologist, immunologist and the head of the molecular biology group at the Centre for DNA Fingerprinting and Diagnostics. Known for her studies on immunosuppression and infection biology, Mukhopadhyay is an elected fellow of all the three major Indian science academies namely the Indian National Science Academy, the Indian Academy of Sciences and the National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded her the National Bioscience Award for Career Development, one of the highest Indian science awards, for her contributions to biosciences in 2008.
Vinay Kumar Nandicoori is an Indian immunologist, biotechnologist and currently the director of Centre for Cellular and Molecular Biology, India. He is known for his studies on the kinase-mediated signaling networks in Mycobacterium tuberculosis, the causative pathogen of tuberculosis. Holder of a master's degree in biotechnology from the Indian Institute of Technology, Bombay and a PhD from the Indian Institute of Science, Nandicoori did his post doctoral work the University of Virginia and Texas A & M University.
Dibyendu Sarkar is an Indian biochemist, molecular microbiologist and a Chief Scientist at the Institute of Microbial Technology. He is known for his studies on Mycobacterium tuberculosis (Mtb), the bacterial pathogen causing the disease of tuberculosis. His studies have been documented by way of a number of articles and Google Scholar, an online repository of scientific articles has listed 23 of them. He has also delivered invited speeches which included the Second Annual Meeting on Infectious Diseases held at the Indian Institute of Science in September 2017. He is an elected member of Guha Research Conference and a recipient of the Raman Research Fellowship of the Council of Scientific and Industrial Research. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2011.
Debasis Dash is an Indian computational biologist and a senior principal scientist at the Institute of Genomics and Integrative Biology (IGIB). Known for his research on Ayurgenomics and extra-pulmonary tuberculosis, his studies have been documented by way of a number of articles and ResearchGate, an online repository of scientific articles has listed 133 of them. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2014.
Ramandeep Singh is an Indian molecular biologist, geneticist and a professor at the Translational Health Science and Technology Institute. Known for his studies on the pathogenesis of Mycobacterium tuberculosis, he is a former research fellow of the National Institutes of Health. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2014.
Dr. Fayaz Ahmad Malik is an Indian pharmacologist, cancer biologist and a scientist at the Indian Institute of Integrative Medicine of the Council of Scientific and Industrial Research. He is known for his studies on investigating the regulatory mechanisms of Cancer Stem Cells during tumor metastasis. His studies also involve the identification of signaling networks conferring resistance to current anti-cancer therapies. His discovery of new anticancer agents holds a number of patents for the processes he has developed. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to Biosciences, in 2014.
Amit Singh is an Indian microbiologist and an associate professor at the department of microbiology and cell biology of the Indian Institute of Science. A Wellcome-DBT Senior Fellow, Singh is known for his studies on the pathogenesis of Mycobacterium tuberculosis. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development for 2017/18. He was awarded with the prestigious CSIR- Shanti Swarup Bhatnagar award on 2021 for his phenomenal contributions in bio-scientific research. He received the 2021 Shanti Swarup Bhatnagar Prize for Science and Technology in Biological Science.
}} Ashwani Kumar is an Indian bacteriologist and the Senior Principal Scientist at the Institute of Microbial Technology (ImTech). He is known for his studies on Mycobacterium tuberculosis, the causative agent of tuberculosis. His laboratory focuses on understanding the reasons for drug tolerance observed in humans. His laboratory hypothesizes that tuberculosis is a biofilm infection, so its treatment needs the administration of multiple drugs for at least six months. The Department of Science and Technology has awarded him Swarnajayanti Fellowship for 2016–2017. Department of Biotechnology has awarded him the National Bioscience Prize (2017-18). He was also selected for DBT/Wellcome Trust India Alliance Senior Fellowship. He was elected as a Fellow of the National Academy of Sciences, India, in 2022.
References
- ↑ "Principal Scientist: Dr. Pawan Gupta". ImTech. 15 May 2018. Retrieved 15 May 2018.
- ↑ "Scientific Staff". ImTech. 15 May 2018. Retrieved 15 May 2018.
- ↑ "Scientist profile". ImTech. 15 May 2018. Retrieved 15 May 2018.
- ↑ "On Google Scholar". Google Scholar. 15 May 2018. Retrieved 15 May 2018.
- ↑ "On ResearchGate". On ResearchGate. 15 May 2018. Retrieved 15 May 2018.
- ↑ "Awardees of National Bioscience Awards for Career Development" (PDF). Department of Biotechnology. 2016. Retrieved 20 November 2017.
