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In cell biology, a phagosome is a vesicle formed around a particle engulfed by a phagocyte via phagocytosis. Professional phagocytes include macrophages, neutrophils, and dendritic cells (DCs).
In biochemistry, an orphan receptor is a protein that has a similar structure to other identified receptors but whose endogenous ligand has not yet been identified. If a ligand for an orphan receptor is later discovered, the receptor is referred to as an "adopted orphan". Conversely, the term orphan ligand refers to a biological ligand whose cognate receptor has not yet been identified.
N-acetyltransferase (NAT) is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines, arylhydroxylamines and arylhydrazines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. N-acetyltransferases are cytosolic enzymes found in the liver and many tissues of most mammalian species, except the dog and fox, which cannot acetylate xenobiotics.
rBCG30 is a prospective Bacillus Calmette-Guérin vaccine against tuberculosis. It is a live vaccine, consisting of BCG, which has been evaluated as a tuberculosis vaccination. It is genetically modified to produce abundant amounts of mycolyl transferase, a 30kDa antigen that has been shown to produce a strong immune response in animals and humans. rBCG30 had been in human clinical trials, but no clinical development has been reported since 2007.
In the field of molecular biology, the pregnane X receptor (PXR), also known as the steroid and xenobiotic sensing nuclear receptor (SXR) or nuclear receptor subfamily 1, group I, member 2 (NR1I2) is a protein that in humans is encoded by the NR1I2 gene.
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Niyaz Ahmed is an Indian molecular epidemiologist, professor of microbial sciences, genomicist, and a veterinarian by training, based in Hyderabad.
Vinod Bhakuni was an Indian molecular biophysicist and the head of the Molecular and Structural Biology Division of the Central Drug Research Institute (CDRI). He was the founder of the Protein Chemistry laboratory of CDRI and was known for his contributions to the study of protein folding. A recipient of the National Bioscience Award for Career Development, he was an elected fellow of the Indian Academy of Sciences, Indian National Science Academy and the National Academy of Sciences, India. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2006, for his contributions to biological sciences.
Javed Naim Agrewala is an Indian immunologist, the prof. at Indian Institute of Technology Ropar and the chief scientist and professor at the Institute of Microbial Technology, Chandigarh. Known for his research on Tuberculosis, Agrewala is an elected fellow of all the three major Indian science academies viz. National Academy of Sciences, India, Indian National Science Academy and Indian Academy of Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 2005. He is also a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology.
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Joyoti Basu is an Indian biochemist, cell biologist and a senior professor at the Bose Institute. Known for her studies on the membrane structure of red blood cells, Basu is an elected fellow of all three major Indian science academies, namely the National Academy of Sciences, India, the Indian Academy of Sciences and the Indian National Science Academy, as well as the Indian Society for Chemical Biology. The Department of Biotechnology of the Government of India awarded her the National Bioscience Award for Career Development, one of the highest Indian science awards, for her contributions to biosciences in 2002.
Nagasuma Chandra is an Indian structural biologist, biochemist and a professor at the department of biochemistry of the Indian Institute of Science. She is known for her studies on Mycobacterium tuberculosis. The Department of Biotechnology of the Government of India awarded her the National Bioscience Award for Career Development, one of the highest Indian science awards, for her contributions to biosciences in 2008.
Vinay Kumar Nandicoori is an Indian immunologist, biotechnologist and currently the director of Centre for Cellular and Molecular Biology, India. He is known for his studies on the kinase-mediated signaling networks in Mycobacterium tuberculosis, the causative pathogen of tuberculosis. Holder of a master's degree in biotechnology from the Indian Institute of Technology, Bombay and a PhD from the Indian Institute of Science, Nandicoori did his post doctoral work the University of Virginia and Texas A & M University.
Dibyendu Sarkar is an Indian biochemist, molecular microbiologist and a Chief Scientist at the Institute of Microbial Technology. He is known for his studies on Mycobacterium tuberculosis (Mtb), the bacterial pathogen causing the disease of tuberculosis. His studies have been documented by way of a number of articles and Google Scholar, an online repository of scientific articles has listed 23 of them. He has also delivered invited speeches which included the Second Annual Meeting on Infectious Diseases held at the Indian Institute of Science in September 2017. He is an elected member of Guha Research Conference and a recipient of the Raman Research Fellowship of the Council of Scientific and Industrial Research. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2011.
Ramandeep Singh is an Indian molecular biologist, geneticist and a professor at the Translational Health Science and Technology Institute. Known for his studies on the pathogenesis of Mycobacterium tuberculosis, he is a former research fellow of the National Institutes of Health. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2014.
Dr. Fayaz Ahmad Malik is an Indian pharmacologist, cancer biologist and a scientist at the Indian Institute of Integrative Medicine of the Council of Scientific and Industrial Research. He is known for his studies on investigating the regulatory mechanisms of Cancer Stem Cells during tumor metastasis. His studies also involve the identification of signaling networks conferring resistance to current anti-cancer therapies. His discovery of new anticancer agents holds a number of patents for the processes he has developed. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to Biosciences, in 2014.
Amit Singh is an Indian microbiologist and an associate professor at the Department of Microbiology and cell biology of the Indian Institute of Science. A Wellcome-DBT Senior Fellow, Singh is known for his studies on the pathogenesis of Mycobacterium tuberculosis. His research focuses on exploring the mechanisms behind the persistence of human pathogens like disease and HIV.
Ashwani Kumar is an Indian microbiologist and the Senior Principal Scientist at the Institute of Microbial Technology (ImTech). He is known for his studies on Mycobacterium tuberculosis, the causative agent of tuberculosis. His laboratory focuses on understanding the reasons for drug tolerance observed in humans. His laboratory hypothesizes that tuberculosis is a biofilm infection, so its treatment needs the administration of multiple drugs for at least six months. The Department of Science and Technology has awarded him Swarnajayanti Fellowship for 2016–2017. Department of Biotechnology has awarded him the National Bioscience Prize (2017-18). He was also selected for DBT/Wellcome Trust India Alliance Senior Fellowship. He was elected as a Fellow of the National Academy of Sciences, India, in 2022. For his contributions in tuberculosis pathogenesis, he was awarded with Shanti Swarup Bhatnagar Prize for Science and Technology 2022. He is considered as one of India's Leading Scientist in the field of Tuberculosis and his lab is doing some of the best research in India.
References
- ↑ "Principal Scientist: Dr. Pawan Gupta". ImTech. 15 May 2018. Retrieved 15 May 2018.
- ↑ "Scientific Staff". ImTech. 15 May 2018. Retrieved 15 May 2018.
- ↑ "Scientist profile". ImTech. 15 May 2018. Retrieved 15 May 2018.
- ↑ "On Google Scholar". Google Scholar. 15 May 2018. Retrieved 15 May 2018.
- ↑ "On ResearchGate". 15 May 2018. Retrieved 15 May 2018.
- ↑ "Awardees of National Bioscience Awards for Career Development" (PDF). Department of Biotechnology. 2016. Retrieved 20 November 2017.
