Pediatric early warning signs

Last updated

Pediatric early warning signs (PEWS) are clinical manifestations that indicate rapid deterioration in pediatric patients, infancy to adolescence. A PEWS score or PEWS system refers to assessment tools that incorporate the clinical manifestations that have the greatest impact on patient outcome. [1]

Contents

Pediatric intensive care is a subspecialty designed for the unique parameters of pediatric patients that need critical care. [2] The first PICU was opened in Europe by Goran Haglund. [3] Over the past few decades, research has proven that adult care and pediatric care vary in parameters, approach, technique, etc. [4] PEWS is used to help determine if a child that is in the Emergency Department should be admitted to the PICU or if a child admitted to the floor should be transferred to the PICU. [5]

It was developed based on the success of MEWS in adult patients to fit the vital parameters and manifestations seen in children.[ citation needed ] The goal of PEWS is to provide an assessment tool that can be used by multiple specialties and units to objectively determine the overall status of the patient. The purpose of this is to improve communication within teams and across fields, recognition time and patient care, and morbidity and mortality rates. [6] Monaghan created the first PEWS based on MEWS, interviews with pediatric nurses, and observation of pediatric patients. [7]

Currently, multiple PEWS systems are in circulation. They are similar in nature, measuring the same domains, but vary in the parameters used to measure the domains. Therefore, some have been proven more effective than others, however, all of them have been statistically significant in improving patient care times and outcomes. [8]

History of pediatric critical care

Pediatric intensive care has been established as a sub-specialty of medicine over the past two decades. It grew out of a need for increasingly complex pediatric care, long-term management of disease, and advancements in medical and surgical sub-specialties, as well as, life-sustaining therapies. [9] The development of pediatric critical care followed the establishment of pediatric intensive care units or PICUs. The first PICU was opened in Europe by Goran Haglund in 1955 at Children's Hospital of Goteburg in Sweden. [10] Advancements in Neonatology and neonatal intensive care, pediatric general surgery, pediatric cardiac surgery, pediatric anesthesiology lead to its opening because of the need to care for critically ill infants and children. Over the next forty years, hundreds of PICUs were established in academic institutions, children's hospitals, and community hospitals. In 1981, the Society of Critical Care Medicine, SCCM, which express guidelines and standards for adult critical care, recognized pediatric critical care as unique from adults and created a separate section within the SSCM for their care. [10] Other institutes followed throughout the 80's, by 1990 there were multiple training programs, certification available, and sub-board on pediatric critical care. [10] Pediatric critical care is now seen as a multidisciplinary field that includes a team of nurse specialists, respiratory therapists, nutritionists, pharmacists, social workers, physical therapists, occupational therapist, and other medical professionals. [11]

Development of pediatric early warning score

To reduce the occurrence of second-rate care, improve outcomes, and enhance quality of life, systems to identify adult patients at risk for rapid clinical deterioration were established based on "early warning signs". These signs brought attention to key clinical parameters that, when affected, encouraged emergent intervention. Modified early warning system (MEWS) is a tool for nurses to help monitor their patients and improve how quickly a rapidly deteriorating client receives the needed care developed from early warning signs. MEWS helps increase objectivity and communication within hospitals. [12]

Patients with progressing critical illness can be predicted and prevented, but failure to identify the signs and lack of prompt intervention for patients developing acute and critical illness remain a problem. Care for them is challenging because children may be asymptomatic until critically ill. Pediatric patients have unique characteristics and different clinical parameters for each age group; adult parameters and concepts cannot be applied to the pediatric patient. Children have greater compensatory mechanisms than adults and can maintain a normal blood pressure despite considerable loss of fluid. For example, a child with sepsis or severe dehydration may seem unaffected and the acute condition is often identified only by the affected vital parameters. [13] However, their condition deteriorates quickly once compensation mechanisms are overwhelmed. In one review, sixty-one percent of pediatric cardiac arrests were caused by respiratory failure and twenty-nine percent by shock, which are both preventable and potentially reversible causes. [14] Thus, to ensure timely care for pediatric patients and improve outcomes, systemic assessment of key symptoms and their severity is essential.

Early recognition and appropriate intervention are equally important in children and may prevent the need for admission to intensive care. Since children seem relatively unaffected until shortly before respiratory failure and cardiac arrest, Monaghan and a group of associates were interested in developing an early warning score system to help nurses assess pediatric patients objectively and improve mortality rates with timely recognition and treatment. They interviewed staff, reviewed MEWS, and conducted research regarding pediatric clinical conditions and markers used to judge severity. Clinical parameters had to be carefully considered due to the uniqueness of the population. For instance, adult systems use blood pressure as one of the main predictors of decline, however, as described, in children hypotension is considered a late sign of shock and multi-system organ failure. Low blood pressure then is a pre-morbid sign and potentially too late for optimum outcomes. [14] The goal was to create an easy-to-use and impartial system that improved outcomes.

Monaghan and his multidisciplinary team created what is referred to as PEWS, pediatric early warning signs. Although still in its early years of use, it is now a standard practice in most hospitals and has already shown to identify children who need a higher level of care, decrease code blue incidents, and improve staff communication and patient safety. In other words, children showing signs of clinical decline are assessed by appropriate medical and nursing staff and receive optimum care during their acute episode. [15]

Pediatric assessment

Normal vital range

Pediatric patients' vital parameters vary by each age group and are different than an adult's healthy range. When reviewing vital signs in each of the age groups, be alert for significant changes and compare with normal values for each of the signs. For best results, when taking vital signs of infants, respirations are counted first before the infant is disturbed, the pulse next, temperature, and then blood pressure last. [16]

Table containing the normal vital parameters of pediatric patients by age group. Vitals.png
Table containing the normal vital parameters of pediatric patients by age group.

Temperature

Temperature should be taken via rectum if the child is under the age of three, for the greatest accuracy, and then orally, unless they are unable to use the oral thermometer properly. Axillary is the least accurate method, but is commonly used when the child is older than three months and the situation is non-concerning or when an accurate oral temperature can't be obtained. [17] Currently, the use of temporal thermometers, that scan the temporal artery, is gaining popularity and is considered accurate for children three months and older. [18]

Heart rate

There are various pulse sites on the body: the carotid, brachial, radial, femoral, and dorsalis pedis. In children, heart rate is preferably taken apically. To count the rate, place stethoscope on the anterior chest at the fifth intercostal space in a midclavicular position. [18] Each "lub-dub" sound is one beat. [19] [20] It should be taken for one full minute, and it should be determined if the rhythm is regular or irregular.

Respirations

The procedure for measuring a child’s respiratory rate is essentially the same as for an adult. Respiration rate may be taken by observing rise and fall, placing your hand and feeling the rise and fall, or using a stethoscope. [21] Since a child’s respiration rate is diaphragmatic, abdominal movement is observed or felt to count the respirations. [18] Like heart rate, respirations should be counted for one full minute.

Blood pressure

The size of the blood pressure cuff is determined by the size of the child's arm or leg. The width of the bladder cuff is two-thirds of the length of the long bone of the extremity on which the blood pressure is taken and the length of the bladder cuff should be about three-fourths the circumference and should not overlap. [18] If the bladder of the cuff is too small, the pressure will be falsely high, and if it is too large, falsely low.

Abnormal findings

Vitals outside of the above parameters are considered abnormal findings. However, before determining additional medical attention is needed, vitals should be repeated to confirm and compared with an individual's baseline assessment. A temperature between 101–102 is considered a mild fever, 102–103 a moderate, and 104 or above a high fever, and delirium or convulsions may occur. From birth until adolescence, temperature between 99.8–100.8 is considered a low-grade fever. If the temperature is taken rectally, it is not considered a fever until it is above 100.4. Once adolescence is reached, it is not considered a fever until 100.4 and if taken rectally, 101. [17] Fever in 3 months and younger is significant and medical referral is needed. Assess the patient to determine if other signs and symptoms are present: flushed face, hot, dry skin, low output, concentrated urine, anorexia, constipation, diarrhea, or vomiting. Older children may complain of sore throat, headaches, aching, and nausea, as well as, other symptoms. [17] Pulse should be checked at distal and proximal sites. Evaluate whether it is normal, bounding, or thready, as well as, compare strength symmetry. Bounding is a stronger than normal pulse and thread a weaker. Unequal pulse is an abnormal finding and indicates a cardiovascular issue. [18] Assess the patient to determine if other signs or symptoms of respiratory – retractions, wheezing, nasal flaring, grunting, etc. -- or cardiac – cyanosis, irritability, edema, etc. -- distress are present. If a child has any acute distress immediate medical intervention is needed. [18]

Pediatric early warning score card Color PEWS.png
Pediatric early warning score card

PEWS models

Pediatrician specialists and others who provide care in this field adapted early warning tools from those in practice with adults with the distinct characteristics of the pediatric population; anatomy, physiology, and clinical manifestations are different in pediatric patients than adult. The goal of pediatric early warning systems is to alert staff to deterioration in pediatric patients at the earliest possibility to quickly intervene and improve mortality rates. [22] It is based on the idea that using objective clinical indicators and risk assessment tools will improve communication and improve patient care, however, there is yet to be a standardized model. A variety of PEWS tools exist with multiple parameters, but all models have three domains in common: cardiovascular, respiratory, and neurological. [23]

Domains

The domains in PEWS represent major body systems that are sensitive to changes in the body and thus create the criteria to be evaluated in a patient to help identify if they are at risk for further deterioration. Parameters on how to measure, such as the importance of including blood pressure, temperature, or nebulizer treatments, change with almost each model. [24] The three domains, cardiovascular, respiratory, and neurological, though are consistently seen throughout each model and have been clinically proven to help identify patients in the emergency department who require admission to the PICU, as well as, assess in advance the need to adapt a care plan to avoid rapid response. [25]

Cardiovascular

Heart rate is commonly used in PEWS, as well as, capillary refill. However, only few use blood pressure because it is not considered as reliable of a measure as the other two. As stated previously, children can maintain a stable blood pressure for much longer than adults. Anatomy and physiology is different in infants and children than adults and vary with age, which produces normal ranges for electrocardiograms. [26] Capillary refill is used across the lifespan as a cardiovascular assessment parameter because it is a non-invasive, quick test to help determine blood flow to the tissues. Heart rate is a crucial piece of assessment in acutely ill pediatric patients because bradycardia may be a sign of conductive tissue dysfunction and lead to sudden death. [27]

Respiratory

Methods in determining a patient's needs related to a respiratory system often requires an accurate health history and a thorough physical examination. Respiratory assessment's are done as part of a comprehensive physical examination or as a focused examination. [28] The judgment in determining whether all or part of the history and physical examination is often completed based on a chief complaint of the patient. [29] Respiratory can be measured by rate, rhythm, characteristics of breathing, and supplemental oxygen use. [30] Different characteristics of breathing are lung sounds, retractions, accessory muscle use, tracheal tug, etc. PEWS uses highly visible and easily monitored characteristics are used, such as retractions, that way there is little variation based on in interpretation. [7] Retractions are a sucking in of the skin around the bones of the chest and illustrate the additional use of muscle to breath, indicated the increased work needed to breath. [31] Similarly, the more supplemental oxygen needed, the less the lungs are providing adequate oxygenation. All of these symptoms indicate respiratory failure, a condition where there is inadequate oxygenation to the body's tissues and organs or inadequate removal of carbon monoxide from the body by the lungs. Left untreated, it is life-threatening. [32]

Neurological

Behavior is typically measured by playing, sleeping, irritable, and confused or reduced response to pain. [33] This is due to the fact it is an age-based assessment and pediatric patients have some form of "playing" as their age appropriate norm. Whether it be gurgling and cooing, coloring, or video games, it is age-specific behavior to a younger population. Irritability in children is often a cue that something is wrong, especially in those unable to communicate verbally due to age or disorder. [18] Other scales simply use level of consciousness as they're neurological assessment, instead of behavior. [34]

Scoring

Nursing interventions associated with different PEWS scores. Correct Color Score.png
Nursing interventions associated with different PEWS scores.

Numbers or color are used in scoring of PEWS. The numbers represent the total score added from the domains (pictured in the above table of Monaghan's design) and the colors are easily understandable "cautions" recognized by most people to help facilitate urgency and in some care settings, communication with patients correlated with numeric scores. [35]

0-2: A score of 0-2 indicates no change in a child's status and regular rounding is acceptable. The plan of care will be continued as is. [35]

3-4: Indicates that a child's care is worsening, but they do not need immediate assistance. The plan of care may change or continued close monitoring will be initiated. [35]

5: The child's status is deteriorating and a change in the plan of care is needed to improve outcomes. This is an urgent situation that requires close monitoring and the involvement of other disciplines.

6+: There are severe consequences if quick intervention is not established, including possible permanent damage or death. A child with a PEWS score of 6+ will mostly be transferred to a PICU to receive the level of critical care they need to improve outcomes with a staff trained to do so. [36]

Application in practice

When implemented, PEWS has had statistically significant impact on multiple units and the care of children. It can identify children admitted to the ED who require admission to the PICU, as well as, help staff assessment of their needs and accurate interventions. [25] It has helped identify more than 75% of code blues within one hour of warning and has the ability to assess more than ten hours earlier the need to adapt a care plan to avoid rapid response. [25] Bedside PEWS, an adopted method for bedside care, can help staff identify when a child is at risk for decline and/or rapidly deteriorating. [37] Also, it has proven to improve staff communication and patient safety. [25]

Limitations

One limitation in the use of PEWS is that there is not a standard model in practice. Doctors and nurses have access to too many variations of how to use the PEWS assessment tool and there is no defined standard. There is over 30 different variations of the assessment tool available to the medical staff to help diagnose PEWS. [23] PEWS provides an easy, objective way to measure a deviation from normal, however, with variation in model, the score is not completely transferable. [23] Another limitation is since this is relatively new, there is little research done on the implementation of PEWS and the effectiveness of its usage.

Citations

  1. Lambert, Veronica; Matthews, Anne; MacDonell, Rachel; Fitzsimons, John (2017). "Paediatric early warning systems for detecting and responding to clinical deterioration in children: a systematic review". BMJ Open . 7 (3): e014497. doi:10.1136/bmjopen-2016-014497. ISSN   2044-6055. PMC   5353324 . PMID   28289051.
  2. Zimmerman, Jerry J.; Anand, Kanwaljeet J. S.; Meert, Kathleen L.; Willson, Douglas F.; Newth, Christopher J. L.; Harrison, Rick; Carcillo, Joseph A.; Berger, John; Jenkins, Tammara L.; Nicholson, Carol; Dean, J. Michael (2016). "Research as a Standard of Care in the PICU*". Pediatric Critical Care Medicine . 17 (1): e13–e21. doi:10.1097/PCC.0000000000000562. ISSN   1529-7535. PMC   5003779 . PMID   26513203.
  3. Epstein, David; Brill, Judith E (2005). "A History of Pediatric Critical Care Medicine". Pediatric Research . 58 (5): 987–996. doi:10.1203/01.PDR.0000182822.16263.3D. ISSN   0031-3998. PMID   16183804 via Nature.
  4. Jarvis, Stuart William; Richardson, Gerry; Flemming, Kate; Fraser, Lorna (2021-11-04). "Estimation of age of transition from children's to adult healthcare for young people with long term conditions using linked routinely collected healthcare data". International Journal of Population Data Science . 6 (1): 1685. doi:10.23889/ijpds.v6i1.1685. ISSN   2399-4908. PMC   8576739 . PMID   34805553.
  5. Gold, Delia L.; Mihalov, Leslie K.; Cohen, Daniel M. (2014). Walthall, Jennifer (ed.). "Evaluating the Pediatric Early Warning Score ( PEWS ) System for Admitted Patients in the Pediatric Emergency Department". Academic Emergency Medicine . 21 (11): 1249–1256. doi:10.1111/acem.12514. ISSN   1069-6563. PMC   4300231 . PMID   25377402.
  6. Agulnik, Asya; Ferrara, Gia; Puerto-Torres, Maria; Gillipelli, Srinithya R.; Elish, Paul; Muniz-Talavera, Hilmarie; Gonzalez-Ruiz, Alejandra; Armenta, Miriam; Barra, Camila; Diaz, Rosdali; Hernandez, Cinthia; Juárez Tobias, Susana; de Jesus Loeza, Jose; Mendez, Alejandra; Montalvo, Erika (2022-03-09). "Assessment of Barriers and Enablers to Implementation of a Pediatric Early Warning System in Resource-Limited Settings". JAMA Network Open . 5 (3): e221547. doi:10.1001/jamanetworkopen.2022.1547. ISSN   2574-3805. PMC   8908074 . PMID   35262714.
  7. 1 2 Johnson, Mary Anbarasi (2023). "Can PHDU Admissions be Reduced or Prevented in Pediatric Set up with PEWS Score Usage? A Case Review" (PDF). Journal of Healthcare and Advanced Nursing. 1 (1): 4. doi:10.59462/JHAN.1.1.102. Archived (PDF) from the original on 2024-04-11. Retrieved 2024-04-11.
  8. Fuijkschot, Joris; Stevens, Jikke; Teheux, Lara; de Loos, Erica; Rippen, Hester; Meurs, Maaike; de Groot, Janke (2023-08-07). "Development of the national Dutch PEWS: the challenge against heterogeneity and implementation difficulties of PEWS in the Netherlands". BMC Pediatrics . 23 (1): 387. doi: 10.1186/s12887-023-04219-3 . ISSN   1471-2431. PMC   10405440 . PMID   37550704.
  9. (Epstein and Brill, 2005, p.987)
  10. 1 2 3 (Epstein and Brill, 2005, p.988)
  11. Levin, Daniel L.; Todres, I. David (2011), "History of Pediatric Critical Care", Pediatric Critical Care, Elsevier, pp. 3–19, doi:10.1016/b978-0-323-07307-3.10001-1, ISBN   978-0-323-07307-3 , retrieved 2024-04-10
  12. "Early Warning Systems: Scorecards That Save Lives". www.ihi.org. Retrieved 2017-10-12.
  13. (Jensen, Aagaard, Olesen, and Kirkegaard, 2017, p.2)
  14. 1 2 (Monaghan, 2005, p.33)
  15. (Monaghan, 2005, p.35)
  16. Sepanski, Robert J.; Godambe, Sandip A.; Zaritsky, Arno L. (2018-03-23). "Pediatric Vital Sign Distribution Derived From a Multi-Centered Emergency Department Database". Frontiers in Pediatrics . 6: 66. doi: 10.3389/fped.2018.00066 . ISSN   2296-2360. PMC   5876311 . PMID   29629363.
  17. 1 2 3 (Agrawal, 2009, p.2)
  18. 1 2 3 4 5 6 7 (Honckenberry and Wilson, 2015)
  19. Raza, Ali; Mehmood, Arif; Ullah, Saleem; Ahmad, Maqsood; Choi, Gyu Sang; On, Byung-Won (2019-11-05). "Heartbeat Sound Signal Classification Using Deep Learning". Sensors . 19 (21): 4819. Bibcode:2019Senso..19.4819R. doi: 10.3390/s19214819 . ISSN   1424-8220. PMC   6864449 . PMID   31694339.
  20. Alanazi, AhmadA; Atcherson, SamuelR; Franklin, CliffordA; Bryan, MelindaF (2020). "Frequency responses of conventional and amplified stethoscopes for measuring heart sounds". Saudi Journal of Medicine and Medical Sciences . 8 (2): 112–117. doi: 10.4103/sjmms.sjmms_118_19 . ISSN   1658-631X. PMC   7305673 . PMID   32587492.
  21. (Agrawal, 2009, p.1)
  22. (Murray, Williams, Pignatarao, and Volpe, 2015, p.166; Fuijkschot et al., 2015, p.15)
  23. 1 2 3 (Murray, Williams, Pignataro, and Volpe, 2015, p.171)
  24. (Murray, Williams, Pignataro, and Volpe, 2015, p.171; Jensen, Aagaard, Olesen, and Kirkegaard, 2017, p.2)
  25. 1 2 3 4 (Murray, Williams, Pignataro, and Volpe, 2015, p.168-170)
  26. (Baruteau et al., 2016, p.151)
  27. (Baruteau et al., 2016, p.152)
  28. Rn), Open Resources for Nursing (Open; Ernstmeyer, Kimberly; Christman, Elizabeth (2021), "Chapter 10 Respiratory Assessment", Nursing Skills [Internet], Chippewa Valley Technical College, retrieved 2024-04-11
  29. Murray, John F.; Davis, J. Lucian (2016). "6". Murray and Nadel's Textbook of Respiratory Medicine (6th ed.). Elsevier. pp. 263–277. doi:10.1016/C2011-1-08123-7. ISBN   978-1-4557-3383-5. PMC   7152492 .
  30. Brinkman, Joshua E.; Toro, Fadi; Sharma, Sandeep (2024), "Physiology, Respiratory Drive", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID   29494021 , retrieved 2024-04-11
  31. Banerjee, Ashis (2017-03-16). Emergency Clinical Diagnosis (1st ed.). Springer Nature. pp. 45–68. doi:10.1007/978-3-319-50718-7_2. ISBN   978-3-319-50718-7. PMC   7122853 via Springer Science+Business Media.
  32. Bhutta, Beenish S.; Alghoula, Faysal; Berim, Ilya (2024), "Hypoxia", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID   29493941 , retrieved 2024-04-11
  33. (Murray, Williams, Pignataro, and Volpe, 2015, p.170)
  34. (Jensen, Aagaard, Olesen, and Kirkegaard, 2017, p.3)
  35. 1 2 3 Branes, Hanne; Solevåg, Anne Lee; Solberg, Marianne Trygg (2020-11-11). "Pediatric early warning score versus a paediatric triage tool in the emergency department: A reliability study". Nursing Open . 8 (2): 702–708. doi:10.1002/nop2.675. PMC   7877131 . PMID   33570310.
  36. Kowalski, Rebecca L.; Lee, Laura; Spaeder, Michael C.; Moorman, J Randall; Keim-Malpass, Jessica (2021-02-22). "Accuracy and Monitoring of Pediatric Early Warning Score (PEWS) Scores Prior to Emergent Pediatric Intensive Care Unit (ICU) Transfer: Retrospective Analysis". JMIR Pediatrics and Parenting. 4 (1): e25991. doi: 10.2196/25991 . PMC   8078697 . PMID   33547772.
  37. (Arke et al., 2010, p.e767)

Related Research Articles

<span class="mw-page-title-main">Pneumonia</span> Inflammation of the alveoli of the lungs

Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. The severity of the condition is variable.

<span class="mw-page-title-main">Sepsis</span> Life-threatening organ dysfunction triggered by infection

Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs.

Palliative care is an interdisciplinary medical caregiving approach aimed at optimizing quality of life and mitigating suffering among people with serious, complex, and often terminal illnesses. Within the published literature, many definitions of palliative care exist. The World Health Organization (WHO) describes palliative care as "an approach that improves the quality of life of patients and their families facing the problems associated with life-threatening illness, through the prevention and relief of suffering by means of early identification and impeccable assessment and treatment of pain, illnesses including other problems whether physical, psychosocial, and spiritual". In the past, palliative care was a disease specific approach, but today the WHO takes a broader patient-centered approach that suggests that the principles of palliative care should be applied as early as possible to any chronic and ultimately fatal illness. This shift was important because if a disease-oriented approach is followed, the needs and preferences of the patient are not fully met and aspects of care, such as pain, quality of life, and social support, as well as spiritual and emotional needs, fail to be addressed. Rather, a patient-centered model prioritizes relief of suffering and tailors care to increase the quality of life for terminally ill patients.

<span class="mw-page-title-main">Extracorporeal membrane oxygenation</span> Technique of providing both cardiac and respiratory support

Extracorporeal membrane oxygenation (ECMO), is a form of extracorporeal life support, providing prolonged cardiac and respiratory support to persons whose heart and lungs are unable to provide an adequate amount of oxygen, gas exchange or blood supply (perfusion) to sustain life. The technology for ECMO is largely derived from cardiopulmonary bypass, which provides shorter-term support with arrested native circulation. The device used is a membrane oxygenator, also known as an artificial lung.

<span class="mw-page-title-main">Acute respiratory distress syndrome</span> Human disease

Acute respiratory distress syndrome (ARDS) is a type of respiratory failure characterized by rapid onset of widespread inflammation in the lungs. Symptoms include shortness of breath (dyspnea), rapid breathing (tachypnea), and bluish skin coloration (cyanosis). For those who survive, a decreased quality of life is common.

In immunology, systemic inflammatory response syndrome (SIRS) is an inflammatory state affecting the whole body. It is the body's response to an infectious or noninfectious insult. Although the definition of SIRS refers to it as an "inflammatory" response, it actually has pro- and anti-inflammatory components.

<span class="mw-page-title-main">Vital signs</span> Group of the 4-6 important medical signs that indicate the status of the bodys vital functions

Vital signs are a group of the four to six most crucial medical signs that indicate the status of the body's vital (life-sustaining) functions. These measurements are taken to help assess the general physical health of a person, give clues to possible diseases, and show progress toward recovery. The normal ranges for a person's vital signs vary with age, weight, sex, and overall health.

A pain scale measures a patient's pain intensity or other features. Pain scales are a common communication tool in medical contexts, and are used in a variety of medical settings. Pain scales are a necessity to assist with better assessment of pain and patient screening. Pain measurements help determine the severity, type, and duration of the pain, and are used to make an accurate diagnosis, determine a treatment plan, and evaluate the effectiveness of treatment. Pain scales are based on trust, cartoons (behavioral), or imaginary data, and are available for neonates, infants, children, adolescents, adults, seniors, and persons whose communication is impaired. Pain assessments are often regarded as "the 5th vital sign".

<span class="mw-page-title-main">SOFA score</span> Medical assessment

The sequential organ failure assessment score, previously known as the sepsis-related organ failure assessment score, is used to track a person's status during the stay in an intensive care unit (ICU) to determine the extent of a person's organ function or rate of failure. The score is based on six different scores, one each for the respiratory, cardiovascular, hepatic, coagulation, renal and neurological systems.

<span class="mw-page-title-main">Intensive care unit</span> Hospital ward that provides intensive care medicine

An intensive care unit (ICU), also known as an intensive therapy unit or intensive treatment unit (ITU) or critical care unit (CCU), is a special department of a hospital or health care facility that provides intensive care medicine.

<span class="mw-page-title-main">Bipolar disorder in children</span>

Bipolar disorder in children, or pediatric bipolar disorder (PBD), is a rare mental disorder in children and adolescents. The diagnosis of bipolar disorder in children has been heavily debated for many reasons including the potential harmful effects of adult bipolar medication use for children. PBD is similar to bipolar disorder (BD) in adults, and has been proposed as an explanation for periods of extreme shifts in mood called mood episodes. These shifts alternate between periods of depressed or irritable moods and periods of abnormally elevated moods called manic or hypomanic episodes. Mixed mood episodes can occur when a child or adolescent with PBD experiences depressive and manic symptoms simultaneously. Mood episodes of children and adolescents with PBD are different from general shifts in mood experienced by children and adolescents because mood episodes last for long periods of time and cause severe disruptions to an individual's life. There are three known forms of PBD: Bipolar I, Bipolar II, and Bipolar Not Otherwise Specified (NOS). The average age of onset of PBD remains unclear, but reported age of onset ranges from 5 years of age to 19 years of age. PBD is typically more severe and has a poorer prognosis than bipolar disorder with onset in late-adolescence or adulthood.

An early warning score (EWS) is a guide used by medical services to quickly determine the degree of illness of a patient. It is based on the vital signs. Scores were developed in the late 1990s when studies showed that in-hospital deterioration and cardiac arrest were often preceded by a period of increasing abnormalities in the vital signs.

<span class="mw-page-title-main">Pediatric intensive care unit</span> Area within a hospital specializing in the care of critically ill infants, children, and teenagers

A pediatric intensive care unit, usually abbreviated to PICU, is an area within a hospital specializing in the care of critically ill infants, children, teenagers, and young adults aged 0–21. A PICU is typically directed by one or more pediatric intensivists or PICU consultants and staffed by doctors, nurses, and respiratory therapists who are specially trained and experienced in pediatric intensive care. The unit may also have nurse practitioners, physician assistants, physiotherapists, social workers, child life specialists, and clerks on staff, although this varies widely depending on geographic location. The ratio of professionals to patients is generally higher than in other areas of the hospital, reflecting the acuity of PICU patients and the risk of life-threatening complications. Complex technology and equipment is often in use, particularly mechanical ventilators and patient monitoring systems. Consequently, PICUs have a larger operating budget than many other departments within the hospital.

Integrated pulmonary index (IPI) is a patient pulmonary index which uses information from capnography and pulse oximetry to provide a single value that describes the patient's respiratory status. IPI is used by clinicians to quickly assess the patient's respiratory status to determine the need for additional clinical assessment or intervention.

Emergence delirium is a condition in which emergence from general anesthesia is accompanied by psychomotor agitation. Some see a relation to pavor nocturnus while others see a relation to the excitement stage of anesthesia.

<span class="mw-page-title-main">Childhood cancer</span> Medical condition

Childhood cancer is cancer in a child. About 80% of childhood cancer cases in high-income countries can be successfully treated thanks to modern medical treatments and optimal patient care. However, only about 10% of children diagnosed with cancer reside in high-income countries where the necessary treatments and care is available. Childhood cancer represents only about 1% of all types of cancers diagnosed in children and adults. For this reason, childhood cancer is often ignored in control planning, contributing to the burden of missed opportunities for its diagnoses and management in countries that are low- and mid-income.

A rapid response system (RRS) is a system implemented in many hospitals designed to identify and respond to patients with early signs of clinical deterioration on non-intensive care units with the goal of preventing respiratory or cardiac arrest. A rapid response system consists of two clinical components, an afferent component, an efferent component, and two organizational components – process improvement and administrative.

Renal angina is a clinical methodology to risk stratify patients for the development of persistent and severe acute kidney injury (AKI). The composite of risk factors and early signs of injury for AKI, renal angina is used as a clinical adjunct to help optimize the use of novel AKI biomarker testing. The term angina from Latin and from the Greek ankhone ("strangling") are utilized in the context of AKI to denote the development of injury and the choking off of kidney function. Unlike angina pectoris, commonly caused due to ischemia of the heart muscle secondary to coronary artery occlusion or vasospasm, renal angina carries no obvious physical symptomatology. Renal angina was derived as a conceptual framework to identify evolving AKI. Like acute coronary syndrome which precedes or is a sign of a heart attack, renal angina is used as a herald sign for a kidney attack. Detection of renal angina is performed by calculating the renal angina index.

Enitan Carrol is a British physician and Professor of Clinical Infection, Microbiology and Immunology. Carrol studies the mechanisms that underpin bacterial infection. In 2020 she was featured in Nicola Rollock's exhibition Phenomenal Women: Portraits of UK Black Female Professors.

A pediatric concussion, also known as pediatric mild traumatic brain injury (mTBI), is a head trauma that impacts the brain capacity. Concussion can affect functional, emotional, cognitive and physical factors and can occur in people of all ages. Symptoms following after the concussion vary and may include confusion, disorientation, lightheadedness, nausea, vomiting, blurred vision, loss of consciousness (LOC) and environment sensitivity. Concussion symptoms may vary based on the type, severity and location of the head injury. Concussion symptoms in infants, children, and adolescents often appear immediately after the injury, however, some symptoms may arise multiple days following the injury leading to a concussion. The majority of pediatric patients recover from the symptoms within one month following the injury. 10-30% of children and adolescents have a higher risk of a delayed recovery or of experiencing concussion symptoms that are persisting.

References