Philip Kantoff | |
---|---|
Nationality | American |
Citizenship | American |
Alma mater | |
Scientific career | |
Institutions | |
Website | Philip Kantoff |
Philip W. Kantoff is a medical oncologist. [2] He is the chairman and chief executive officer (CEO) of Convergent Therapeutics. [3] He served as the Chairman of Medicine at Memorial Sloan Kettering Cancer Center between 2015 and 2021. [4] [5] He is best known for his contributions to the impact of DNA abnormalities in prostate cancer and the discovery of therapies for metastatic hormone-sensitive prostate cancer.
Kantoff grew up in Forest Hills, New York City. [6] He attended Brown University, where he earned his undergraduate and medical degrees through the Program in Liberal Medical Education. [6] He completed his residency in internal medicine at New York University/Bellevue Hospital, followed by a post doctorate at the National Institutes of Health. He then completed his fellowship in medical oncology at the Dana–Farber Cancer Institute. [6]
Kantoff joined the Dana–Farber Cancer Institute in a full-time position in genitourinary oncology in 1988. He held various roles at Dana-Farber, including director of the Lank Center for Genitourinary Oncology, chief of the Division of Solid Tumor Oncology, and head of the Prostate Cancer Program. [6] He was named the inaugural Nancy and Jerome Kohlberg Professor at Harvard Medical School in 2014. [5]
While at Dana-Farber, he also served as the lead investigator for Dendreon's clinical trials for Sipuleucel-T, a therapeutic vaccine for prostate cancer approved in 2010. [7] After 28 years at Dana-Farber, Kantoff joined Memorial Sloan Kettering Cancer Center in 2015 to replace George J. Bosl as the Chairman of Medicine. He serves as a Professor of Medicine at the Weill Cornell Medical College. [5] Kantoff won two 2018 Prostate Cancer Foundation Challenge Awards, one on Clonal Hematopoiesis and Prostate Cancer and another alongside fellow principal investigator Mark Pomerantz on DNA Damage Repair Alternations in Prostate Cancer. [8] He was also awarded an NCI SPORE grant for prostate cancer from 2001 to 2015 and a NCI Program Project Grant in 2019 on DNA Damage Repair Alterations in Prostate Cancer. In 2018, Kantoff became an independent director at Context Therapeutics. [9] [10]
In 2021, Kantoff was appointed chairman and chief executive officer of Convergent Therapeutics, a pharmaceutical company based in Cambridge, Massachusetts that focuses on radiopharmaceutical cancer therapies. [3] In 2022, Kantoff joined the board of directors of ESSA Pharma. [11]
Josep Baselga i Torres, known in Spanish as José Baselga, was a Spanish medical oncologist and researcher focused on the development of novel molecular targeted agents, with a special emphasis in breast cancer. Through his career he was associated with the Memorial Sloan Kettering Cancer Center, Vall d'Hebron Institute of Oncology, and the Massachusetts General Hospital in their hematology and oncology divisions. He led the development of the breast cancer treatment Herceptin, a monoclonal antibody, that targets the HER2 protein, which is impacted in aggressive breast cancers.
The Society for Immunotherapy of Cancer (SITC), previously known as the International Society for Biological Therapy of Cancer (iSBTc), is a professional society of scientists, academicians, researchers, clinicians, government representatives, and industry leaders from around the world dedicated to improving outcomes in patients with cancer by advancing the science and application of cancer immunotherapy. Currently, SITC has more than 2,400 members, representing 22 medical specialties from 42 countries around the world, who are engaged in the research and treatment of cancer.
William K. Oh, is an American medical oncologist, academic and industry leader and expert in the management of genitourinary malignancies, including prostate, renal, bladder and testicular cancers.
Sipuleucel-T, sold under the brand name Provenge, developed by Dendreon Pharmaceuticals, LLC, is a cell-based cancer immunotherapy for prostate cancer (CaP). It is an autologous cellular immunotherapy.
Simon N. Powell is a British cancer researcher and radiation oncologist residing in New York City.
Peter T. Scardino is an American cancer surgeon, researcher, and author expert in genitourinary and urological cancers particularly cancer of the prostate. He is chair of the Department of Surgery at Memorial Sloan Kettering Cancer Center.
Kenneth Offit is an American cancer geneticist and oncologist known for his discoveries with respect to the genetic bases of breast, colorectal, and lymphoid cancers. He is currently Chief of the Clinical Genetics Service and the Robert and Kate Niehaus Chair in Inherited Cancer Genomics at Memorial Sloan Kettering Cancer Center. Offit is also a member of the Program in Cancer Biology and Genetics at the Sloan-Kettering Institute and Professor of Medicine and Healthcare Policy and Research at Weill Cornell Medical College. He was previously a member of both the Board of Scientific Counselors of the National Cancer Institute and the Evaluation of Genomic Applications in Practice and Prevention working group of the U.S. Centers for Disease Control.
PROSTVAC is a cancer immunotherapy candidate in clinical development by Bavarian Nordic for the treatment of all prostate cancer although clinical trials are focusing on more advanced cases of metastatic castration-resistant prostate cancer (mCRPC). PROSTVAC is a vaccine designed to enable the immune system to recognize and attack prostate cancer cells by triggering a specific and targeted T cell immune response to cancer cells that express the tumor-associated antigen prostate-specific antigen (PSA).
Maurie Markman is a physician and the President of Medicine & Science, City of Hope National Medical Center Atlanta, Chicago and Phoenix. He was previously the President of Medicine and Science at Cancer Treatment Centers of America and the Vice President for Clinical Research at M.D. Anderson Cancer Center at the University of Texas. In 1992 he was appointed the first Director of the Taussig Cancer Center at the Cleveland Clinic, a position he held for 12 years. During that time he was also Professor of Medicine and the Chairman of the Department of Hematology/Oncology at the Cleveland Clinic. He has also held appointments on the faculty of Memorial Sloan Kettering Cancer Center in NYC and Moores Cancer Center at the University of California, San Diego. He was named a "Giant of Cancer Care" in 2018 by OncLive.
Howard I. Scher is the Chief of the Genitourinary Oncology at Memorial Sloan Kettering Cancer Center and Professor of Medicine at the Weill Cornell Medical College. He has a depth of experience in clinical trials for novel types of cancer treatment.
Nathanael S. Gray is an American chemist. He serves as Krishnan-Shah Family Professor of chemical and systems biology at Stanford University and director of cancer therapeutics programme at Stanford University School of Medicine. Previously he was a Nancy Lurie Marks Professor of biological chemistry and molecular pharmacology at Harvard Medical School and professor of cancer biology at Dana–Farber Cancer Institute. Gray is also co-founder, science advisory board member (SAB) and equity holder in C4 Therapeutics, Gatekeeper, Syros, Petra, B2S, Aduro, Jengu, Allorion, Inception Therapeutics, and Soltego. C4 Therapeutics, which offered IPO in 2020, was founded based on the research of Jay Bradner, current president of Novartis Institutes for BioMedical Research (NIBR), and of Nathanael S. Gray, while he was professor at Harvard Medical School. Before moving to Stanford University, Nathanael S. Gray created Center for Protein Degradation at Harvard Medical School with $80 million agreement with Deerfield Management venture capital firm. In 2020, Gray Lab permanently moved to Stanford University, that was stated by Stuart Schreiber, co-founder of Broad Institute as "Stanford's huge gain".
Mary-Ellen Taplin, is a research oncologist at Dana Farber Cancer Institute and Brigham and Women's Hospital in Harvard's Longwood Medical and Academic Area.
Luis Alberto Diaz, Jr. is the Head of the Division of Solid Tumor Oncology in Memorial Sloan Kettering’s Department of Medicine.
Judy Ellen Garber is the director of the Center for Cancer Genetics and Prevention at the Dana–Farber Cancer Institute and a professor of medicine at Harvard Medical School. Garber previously served as president of the American Association for Cancer Research.
Padmanee Sharma is an immunologist and oncologist at the University of Texas MD Anderson Cancer Center in Houston, Texas. She holds the position of professor of genitourinary medical oncology and immunology in the Division of Cancer Medicine where she specializes in renal, prostate, and bladder cancers.
Kornelia Polyak is a professor of medicine at Harvard Medical School and an internationally recognized breast cancer expert.
Levi A. Garraway is an American oncologist. His research team was among the first to adapt genomics technologies to enable scalable, high-throughput clinical approaches to cancer gene mutation profiling. As a result, he was inducted into the American Society for Clinical Investigation, American Association for Cancer Research, and National Academy of Medicine.
Matthew Langer Meyerson is an American pathologist and the Charles A. Dana Chair in Human Cancer Genetics at the Dana-Farber Cancer Institute. He is also director of the Center for Cancer Genomics at the Dana-Farber Cancer Institute, and the Director of Cancer Genomics at the Broad Institute of MIT and Harvard.
Nancy Lin is an American oncologist who works at the Dana-Farber Cancer Institute and is an Associate Professor of Medicine at Harvard Medical School. Her research considers new diagnostic strategies and treatment pathways for HER2 positive breast cancer.
Deborah Schrag is the George H. Bosl Chair at Memorial Sloan Kettering Cancer Center. She is a medical oncologist known for her work in patient care and examination of patient outcomes.