Phosphohydroxypyruvic acid

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Phosphohydroxypyruvic acid
Phosphohydroxypyruvic acid.svg
Names
Preferred IUPAC name
2-Oxo-3-(phosphonooxy)propanoic acid
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.164.559 OOjs UI icon edit-ltr-progressive.svg
KEGG
MeSH Phosphohydroxypyruvic+acid
PubChem CID
UNII
  • InChI=1S/C3H5O7P/c4-2(3(5)6)1-10-11(7,8)9/h1H2,(H,5,6)(H2,7,8,9)
    Key: LFLUCDOSQPJJBE-UHFFFAOYSA-N
  • C(C(=O)C(=O)O)OP(=O)(O)O
Properties
C3H5O7P
Molar mass 184.040 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Phosphohydroxypyruvic acid is an organic acid most widely known as an intermediate in the synthesis of serine. [1]

It is produced from 3-phosphoglyceric acid by the action of the enzyme phosphoglycerate dehydrogenase. [2]

D-3-Phosphoglycerinsaure.svg
3-phosphoglyceric acid
+ NAD+
 
 
 
H+
Phosphohydroxypyruvic acid
 
H+
 
3-Phosphonooxypyruvic acid.svg
phosphohydroxypyruvic acid
+ NADH
 

References

  1. ↑ Igamberdiev, Abir U.; Kleczkowski, Leszek A. (2018). "The Glycerate and Phosphorylated Pathways of Serine Synthesis in Plants: The Branches of Plant Glycolysis Linking Carbon and Nitrogen Metabolism". Frontiers in Plant Science. 9: 318. doi: 10.3389/fpls.2018.00318 . PMC   5861185 . PMID   29593770.
  2. ↑ Enzyme 1.1.1.95 at KEGG Pathway Database.
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