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| Formula | C25H46N4O4 |
| Molar mass | 466.667 g·mol−1 |
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Prethcamide (trade name Micoren) is a respiratory stimulant composed of two related drugs, cropropamide and crotethamide. It was developed by Ciba-Geigy. [1] [2]
Novartis AG is a Swiss multinational pharmaceutical corporation based in Basel, Switzerland. Consistently ranked in the global top five, Novartis is one of the largest pharmaceutical companies in the world and was the fourth largest by revenue in 2022.
The Toms River is a 41.7-mile-long (67.1 km) freshwater river and estuary in Ocean County, New Jersey, United States. The river rises in the Pine Barrens of northern Ocean County, then flows southeast and east, where it is fed by several tributaries, and flows in a meandering course through wetlands. The river empties into Barnegat Bay—an inlet of the Atlantic Ocean—and the Intracoastal Waterway at Mile 14.6.
Paul Hermann Müller, also known as Pauly Mueller, was a Swiss chemist who received the 1948 Nobel prize in Physiology or Medicine for his 1939 discovery of insecticidal qualities and use of DDT in the control of vector diseases such as malaria and yellow fever.
Omalizumab, sold under the brand name Xolair among others, is an injectable medication to treat severe persistent allergic forms of asthma, nasal polyps, urticaria (hives), and immunoglobulin E-mediated food allergy.
Diazinon, a colorless to dark brown liquid, is a thiophosphoric acid ester developed in 1952 by Ciba-Geigy, a Swiss chemical company. It is a nonsystemic organophosphate insecticide formerly used to control cockroaches, silverfish, ants, and fleas in residential, non-food buildings. Diazinon was heavily used during the 1970s and early 1980s for general-purpose gardening use and indoor pest control. A bait form was used to control scavenger wasps in the western U.S. Diazinon is used in flea collars for domestic pets in Australia and New Zealand. Diazinon is a major component in the "Golden Fleece" brand sheep dip. Residential uses of diazinon were outlawed in the U.S. in 2004 because of human health risks but it is still approved for agricultural uses. An emergency antidote is atropine.
Spermidine is a polyamine compound found in ribosomes and living tissues and having various metabolic functions within organisms.
Chloropyramine is a classical first-generation antihistamine drug approved in Eastern European countries for the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Related indications for clinical use include angioedema, allergic reactions to insect bites, food and drug allergies, and anaphylactic shock.
Frank Henry Netter was an American surgeon and medical illustrator. The first edition of his Atlas of Human Anatomy — his "personal Sistine Chapel" — was published in 1989; he was a fellow of the New York Academy of Medicine where he was first published in 1957.
Tripelennamine, sold under the brand name Pyribenzamine by Novartis, is a drug that is used as an antipruritic and first-generation antihistamine. It can be used in the treatment of asthma, hay fever, rhinitis, and urticaria, but is now less common as it has been replaced by newer antihistamines. The drug was patented at CIBA, which merged with Geigy into Ciba-Geigy, and eventually becoming Novartis.
Phenformin is an antidiabetic drug from the biguanide class. It was marketed as DBI by Ciba-Geigy, but was withdrawn from most markets in the late 1970s due to a high risk of lactic acidosis, which was fatal in 50% of cases.
Talizumab (TNX-901) is a humanized monoclonal antibody that was under development by Tanox in Houston, Texas as a new-concept therapeutic for allergic diseases. The unique anti-IgE antibody was designed to target immunoglobulin E (IgE) and IgE-expressing B lymphocytes specifically, without binding to IgE already bound by the high affinity IgE receptors on mast cells and basophils. Talizumab was tested in clinical trials at National Jewish Medical and Research Center and other medical centers and allergy clinics across the U. S. and shown to be able to prevent allergic reactions to accidental exposure to peanuts, which is contained in many kinds of foods.
Traugott Sandmeyer was a Swiss chemist after whom the Sandmeyer reaction, which he discovered 1884, was named.
Cefroxadine is a cephalosporin antibiotic. It is structurally related to cefalexin, and both drugs share a similar spectrum of activity.
Indoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It was withdrawn worldwide in the 1980s after postmarketing reports of severe gastrointestinal bleeding.
Pirprofen was a nonsteroidal anti-inflammatory drug (NSAID) that was brought to market by Ciba-Geigy in 1982 as a treatment for arthritis and pain. Its label was restricted after adverse events arose, including some cases of fatal liver toxicity. Ciba-Geigy voluntarily withdrew the drug from the market worldwide in 1990.
Markus Eduard Fierz was a Swiss physicist, particularly remembered for his formulation of spin–statistics theorem, and for his contributions to the development of quantum theory, particle physics, and statistical mechanics. He was awarded the Max Planck Medal in 1979 and the Albert Einstein Medal in 1989 for all his work.
Montanic acid is a saturated fatty acid isolated and detected mainly in montan wax. It also occurs in beeswax and Chinese wax. Montanic acid ethylene glycol esters and glycerol esters are used as protective layer on fruit skins and coating on foods. It is known as E number reference E912.
The life sciences industry in Switzerland directly and indirectly employs about 135,000 people. It contributes 5.7% of the gross domestic product of Switzerland and 30% of the country's exports. In 2017 about 30% of Swiss exports were chemical products. In the same year Switzerland was the second largest exporter of packaged medicine in the world, with about 11% of the global total, worth $36.5 billion.
Rudolf Geigy was a Swiss biologist and a professor of embryology and genetics at the University of Basel. He established the Swiss Tropical and Public Health Institute and studied tropical diseases.
Difluorodiphenyltrichloroethane (DFDT) is a chemical compound. Its composition is the same as that of the insecticide DDT, except that two of DDT's chlorine atoms are replaced by two fluorine atoms.
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