Proline rich 11

PRR11
Identifiers
Aliases	PRR11 , proline rich 11
External IDs	OMIM: 615920; MGI: 2444496; HomoloGene: 10123; GeneCards: PRR11; OMA:PRR11 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	59,206,709 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	86,999,534 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; renal medulla; ; cardia; ; pylorus; ; nipple; ; superior surface of tongue; ; ventral tegmental area; ; buccal mucosa cell; ; trigeminal ganglion; ; inferior ganglion of vagus nerve;
	Top expressed in
	tail of embryo; ; genital tubercle; ; ventricular zone; ; hand; ; epiblast; ; cumulus cell; ; granulocyte; ; primitive streak; ; morula; ; thymus;
	More reference expression data
	n/a
Orthologs
	55771
	270906
	ENSG00000068489
	ENSMUSG00000020493
	Q96HE9
	Q8BHE0
	NM_018304
	NM_175563
	NP_060774 ; NP_060774.2
	NP_780772
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated November 09, 2024

Proline rich 11 is a protein that in humans is encoded by the PRR11 gene. ^[5]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000068489 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020493 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Proline rich 11" . Retrieved 2017-11-15.

Szafranski K, Schindler S, Taudien S, Hiller M, Huse K, Jahn N, Schreiber S, Backofen R, Platzer M (2007). "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns". Genome Biol. 8 (8): R154. doi: 10.1186/gb-2007-8-8-r154 . PMC 2374985 . PMID 17672918.
Ji Y, Xie M, Lan H, Zhang Y, Long Y, Weng H, Li D, Cai W, Zhu H, Niu Y, Yang Z, Zhang C, Song F, Bu Y (2013). "PRR11 is a novel gene implicated in cell cycle progression and lung cancer". Int. J. Biochem. Cell Biol. 45 (3): 645–56. doi:10.1016/j.biocel.2012.12.002. PMID 23246489.
Zhang C, Zhang Y, Li Y, Zhu H, Wang Y, Cai W, Zhu J, Ozaki T, Bu Y (2015). "PRR11 regulates late-S to G2/M phase progression and induces premature chromatin condensation (PCC)". Biochem. Biophys. Res. Commun. 458 (3): 501–8. doi:10.1016/j.bbrc.2015.01.139. PMID 25666944.
Zhou F, Liu H, Zhang X, Shen Y, Zheng D, Zhang A, Lai Y, Li H (2014). "Proline-rich protein 11 regulates epithelial-to-mesenchymal transition to promote breast cancer cell invasion". Int J Clin Exp Pathol. 7 (12): 8692–9. PMC 4314043 . PMID 25674234.
Chen Y, Cha Z, Fang W, Qian B, Yu W, Li W, Yu G, Gao Y (2015). "The prognostic potential and oncogenic effects of PRR11 expression in hilar cholangiocarcinoma". Oncotarget. 6 (24): 20419–33. doi:10.18632/oncotarget.3983. PMC 4653015 . PMID 25971332.
Zhao Q (2015). "RNAi-mediated silencing of praline-rich gene causes growth reduction in human lung cancer cells". Int J Clin Exp Pathol. 8 (2): 1760–7. PMC 4396257 . PMID 25973065.
Wang Y, Zhang Y, Zhang C, Weng H, Li Y, Cai W, Xie M, Long Y, Ai Q, Liu Z, Du G, Wang S, Niu Y, Song F, Ozaki T, Bu Y (2015). "The gene pair PRR11 and SKA2 shares a NF-Y-regulated bidirectional promoter and contributes to lung cancer development". Biochim. Biophys. Acta. 1849 (9): 1133–44. doi:10.1016/j.bbagrm.2015.07.002. PMID 26162986.
Song Z, Liu W, Xiao Y, Zhang M, Luo Y, Yuan W, Xu Y, Yu G, Hu Y (2015). "PRR11 Is a Prognostic Marker and Potential Oncogene in Patients with Gastric Cancer". PLOS ONE. 10 (8): e0128943. Bibcode:2015PLoSO..1028943S. doi: 10.1371/journal.pone.0128943 . PMC 4529228 . PMID 26252227.
Wang Y, Weng H, Zhang Y, Long Y, Li Y, Niu Y, Song F, Bu Y (2017). "The PRR11-SKA2 Bidirectional Transcription Unit Is Negatively Regulated by p53 through NF-Y in Lung Cancer Cells". Int J Mol Sci. 18 (3): 534. doi: 10.3390/ijms18030534 . PMC 5372550 . PMID 28257042.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000068489 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020493 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Proline rich 11" . Retrieved 2017-11-15.

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Proline rich 11

Related Research Articles

References

Further reading