Protein DEPP

Last updated
DEPP1
Identifiers
Aliases DEPP1 , DEPP, FIG, Fseg, chromosome 10 open reading frame 10, autophagy regulator, C10orf10, DEPP1 autophagy regulator
External IDs OMIM: 611309 MGI: 1918730 HomoloGene: 48491 GeneCards: DEPP1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007021

NM_001166580
NM_145980

RefSeq (protein)

NP_008952

NP_001160052
NP_666092

Location (UCSC) Chr 10: 44.97 – 44.98 Mb Chr 6: 116.63 – 116.63 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protein DEPP also known as decidual protein induced by progesterone (DEPP) and fasting-induced gene protein (FIG) is a protein that in humans is encoded by the DEPP gene. [5]

Contents

Function

The expression of this gene is induced by fasting as well as by progesterone. The protein encoded by this gene contains a t-synaptosome-associated protein receptor (SNARE) coiled-coil homology domain and a peroxisomal targeting signal. Production of the encoded protein leads to phosphorylation and activation of the transcription factor ELK1. [5]

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000165507 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000048489 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: C10orf10 chromosome 10 open reading frame 10".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.