PsychENCODE Consortium

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The PsychENCODE Consortium was founded by the U.S. National Institutes of Health in 2015 to study the role of rare genetic variants involved in several psychiatric disorders. PsychENCODE aims to create a public resource of genomic data gathered from 1,000 healthy and disease-affected post-mortem brains reflecting different developmental periods.

PsychENCODE will first focus on autism spectrum disorder, bipolar disorder, and schizophrenia, and then move on to other disorders. [1]

Bipolar disorder mental disorder that causes periods of depression and periods of abnormally elevated mood

Bipolar disorder, previously known as manic depression, is a mental disorder that causes periods of depression and periods of abnormally elevated mood. The elevated mood is significant and is known as mania or hypomania, depending on its severity, or whether symptoms of psychosis are present. During mania, an individual behaves or feels abnormally energetic, happy, or irritable. Individuals often make poorly thought out decisions with little regard to the consequences. The need for sleep is usually reduced during manic phases. During periods of depression, there may be crying, a negative outlook on life, and poor eye contact with others. The risk of suicide among those with the illness is high at greater than 6 percent over 20 years, while self-harm occurs in 30–40 percent. Other mental health issues such as anxiety disorders and substance use disorder are commonly associated with bipolar disorder.

Schizophrenia Mental disorder characterized by abnormal behavior and misinterpretation of reality

Schizophrenia is a mental disorder characterized by abnormal behavior, strange speech, and a decreased ability to understand reality. Other symptoms include false beliefs, unclear or confused thinking, hearing voices that do not exist, reduced social engagement and emotional expression, and lack of motivation. People with schizophrenia often have additional mental health problems such as anxiety, depression, or substance-use disorders. Symptoms typically come on gradually, begin in young adulthood, and, in many cases, never resolve.

Participating organizations

As of December 2018, participating organizations include:

Duke University Private university in Durham, North Carolina, United States

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Icahn School of Medicine at Mount Sinai medical school

The Icahn School of Medicine at Mount Sinai (ISMMS), formerly Mount Sinai School of Medicine, is a graduate medical school in Manhattan, New York City.

Johns Hopkins University Private research university in Baltimore, Maryland

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University of California, San Francisco university

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University at Buffalo Public research university in Buffalo, New York

The State University of New York at Buffalo is a public research university with campuses in Buffalo and Amherst, New York, United States. It is commonly referred to as SUNY Buffalo or the University at Buffalo (UB), and was formerly known as the University of Buffalo. It is the de facto flagship campus of the State University of New York (SUNY) system, with the largest enrollment, largest endowment and research funding as a comprehensive university center in the SUNY system. The university was founded in 1846 as a private medical college, but in 1962 merged with the SUNY system.

State University of New York at Canton

The State University of New York at Canton is a public, coeducational, residential college located in the Town of Canton in St. Lawrence County, New York, United States. Its northern location places it close to the Adirondack Mountains, the St. Lawrence River, and major Canadian cities such as Ottawa and Montreal.

Institute of Psychiatry, Psychology and Neuroscience research school of Kings College London, England

The Institute of Psychiatry, Psychology and Neuroscience (IoPPN) is a research institution dedicated to discovering what causes mental illness and diseases of the brain. In addition, its aim is to help identify new treatments for them and ways to prevent them in the first place. The IoPPN is a school of King's College London, England, previously known as Institute of Psychiatry (IoP).

SUNY Downstate Medical Center Hospital in New York City, United States

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UC Davis Medical Center Hospital in California, United States

UC Davis Medical Center, formerly known as Sacramento Medical Center, is a major academic health center located in Sacramento, California. It is owned and operated by the University of California as part of its University of California, Davis campus. The medical center sits on a 142-acre (57 ha) campus located between the Elmhurst, Tahoe Park, and Oak Park residential neighborhoods. The site incorporates the land and some of the buildings of the former Sacramento Medical Center as well as much of the land previously occupied by the California State Fair until its 1967 move to a new location.

UC San Diego Health Hospital in San Diego, California

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Western University of Health Sciences

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SUNY Upstate Medical University often referred to as "Upstate"

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Ian Ainsworth Cook is an American psychiatrist. He is an associate professor of Psychiatry and Biobehavioral Sciences at the University of California, Los Angeles's David Geffen School of Medicine. He is also a research scientist at the UCLA Neuropsychiatric Institute and the Brain Research Institute at UCLA. He serves as director of the UCLA Depression Research Program and associate director of the UCLA Laboratory of Brain, Behavior, and Pharmacology. Cook holds the Joanne and George Miller & Family Chair in Depression Research.

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Esther Somerfeld-Ziskind Esther Somerfeld-Ziskind was a pioneering researcher into insulin, lithium, and electroconvulsive therapy.

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Huda Zoghbi Lebanese scientist

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University at Buffalo School of Medicine and Biomedical Sciences

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BPDFamily.com is an online support group for the family members of individuals with borderline personality disorder (BPD). The group is one of the first "cyber" support groups to be recognized by the medical providers and receive professional referrals.

Kristine Yaffe American scholar

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Richard Bryant (psychologist) Australian psychologist

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References

  1. Akbarian, S; Liu, C; Knowles, JA (2015). "The PsychENCODE project". Nat Neurosci. 18: 1707–12. doi:10.1038/nn.4156. PMC   4675669 . PMID   26605881.
  2. "PsychENCODE". psychENCODE.org. Retrieved 2018-12-26.