RAB14

RAB14
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1Z0F, 4D0G, 4DRZ
Identifiers
Aliases	RAB14 , FBP, RAB-14, member RAS oncogene family
External IDs	OMIM: 612673 MGI: 1915615 HomoloGene: 48679 GeneCards: RAB14
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q33.2 Start 121,178,133 bp [1] End 121,223,014 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 B Start 35,070,217 bp [2] End 35,091,132 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in nipple inferior ganglion of vagus nerve lactiferous duct lower lobe of lung ventral tegmental area optic nerve frontal pole superior vestibular nucleus renal medulla trigeminal ganglion Top expressed in ciliary body conjunctival fornix fossa iris retinal pigment epithelium condyle urothelium medullary collecting duct barrel cortex sexually immature organism More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GDP binding GTP binding myosin V binding protein binding GTPase activity Cellular component recycling endosome endosome late endosome rough endoplasmic reticulum nuclear outer membrane-endoplasmic reticulum membrane network intracellular membrane-bounded organelle membrane Golgi membrane intracellular anatomical structure lysosomal membrane trans-Golgi network phagocytic vesicle perinuclear region of cytoplasm Golgi stack trans-Golgi network transport vesicle lysosome extracellular exosome cytoplasmic vesicle cytosol plasma membrane cilium early endosome membrane recycling endosome membrane tertiary granule membrane early endosome Golgi apparatus Biological process embryo development Golgi to endosome transport intracellular transport fibroblast growth factor receptor signaling pathway phagosome maturation defense response to bacterium endocytic recycling protein transport vesicle-mediated transport regulation of protein localization phosphatidylinositol biosynthetic process neutrophil degranulation regulation of endocytosis transport intracellular protein transport Rab protein signal transduction regulation of embryonic development phagolysosome assembly involved in apoptotic cell clearance Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51552 68365 Ensembl ENSG00000119396 ENSMUSG00000026878 UniProt P61106 Q91V41 RefSeq (mRNA) NM_016322 NM_026697 RefSeq (protein) NP_057406 NP_080973 Location (UCSC) Chr 9: 121.18 – 121.22 Mb Chr 2: 35.07 – 35.09 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ras-related protein Rab-14 is a protein that in humans is encoded by the RAB14 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000119396 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026878 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. de Leeuw HP, Koster PM, Calafat J, Janssen H, van Zonneveld AJ, van Mourik JA, Voorberg J (Dec 1998). "Small GTP-binding proteins in human endothelial cells". Br J Haematol. 103 (1): 15–9. doi:10.1046/j.1365-2141.1998.00965.x. PMID   9792283. S2CID   24857520.
6. Junutula JR, De Maziere AM, Peden AA, Ervin KE, Advani RJ, van Dijk SM, Klumperman J, Scheller RH (Apr 2004). "Rab14 is involved in membrane trafficking between the Golgi complex and endosomes". Mol Biol Cell. 15 (5): 2218–29. doi:10.1091/mbc.E03-10-0777. PMC   404017 . PMID   15004230.
7. "Entrez Gene: RAB14 RAB14, member RAS oncogene family".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID   8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC   139146 . PMID   9110174.
• Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi: 10.1073/pnas.160270997 . PMC   16901 . PMID   10931946.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Garin J, Diez R, Kieffer S, et al. (2001). "The phagosome proteome: insight into phagosome functions". J. Cell Biol. 152 (1): 165–80. doi:10.1083/jcb.152.1.165. PMC   2193653 . PMID   11149929.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Predic J, Soskic V, Bradley D, Godovac-Zimmermann J (2002). "Monitoring of gene expression by functional proteomics: response of human lung fibroblast cells to stimulation by endothelin-1". Biochemistry. 41 (3): 1070–8. doi:10.1021/bi0117854. PMID   11790131.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC   2734081 . PMID   15164053.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID   15761153. S2CID   39457788.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.