RAB15

RAB15
Identifiers
Aliases	RAB15 , member RAS oncogene family
External IDs	HomoloGene: 131279 GeneCards: RAB15
Gene location (Human)
Chr.	Chromosome 14 (human)
End	64,973,226 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; cingulate gyrus; ; endothelial cell; ; parotid gland; ; middle temporal gyrus; ; superior frontal gyrus; ; oocyte; ; Brodmann area 46;
	n/a
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding ; GTP binding ; protein binding ; GTPase activity ;
Cellular component	cytoplasm ; perinuclear region of cytoplasm ; plasma membrane ; endosome membrane ; extracellular exosome ; membrane ; cilium ; endosome ; synaptic vesicle ;
Biological process	protein transport ; positive regulation of regulated secretory pathway ; vesicle docking involved in exocytosis ; protein secretion ; transport ; intracellular protein transport ; regulation of exocytosis ; Rab protein signal transduction ; protein localization to plasma membrane ;
	Sources:Amigo / QuickGO
Orthologs
	376267
	n/a
	ENSG00000139998
	n/a
	P59190
	n/a
	NM_001308154 ; NM_198686 ; NM_001330182
	n/a
	NP_001295083 ; NP_001317111 ; NP_941959
	n/a
	Wikidata
View/Edit Human

Last updated January 12, 2024

Ras-related protein Rab-15 is a protein that in humans is encoded by the RAB15 gene.^[3]^[4]

Related Research Articles

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Ras-related protein Rab-13 is a protein that in humans is encoded by the RAB13 gene.

Regulating synaptic membrane exocytosis protein 2 is a protein that in humans is encoded by the RIMS2 gene.

Ras-related protein Rab-3D is a protein that in humans is encoded by the RAB3D gene.

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Ras-related protein Rab-40A is a protein that in humans is encoded by the RAB40A gene.

Synaptotagmin-4 is a protein that in humans is encoded by the SYT4 gene.

Ras-related protein Rab-5C is a protein that in humans is encoded by the RAB5C gene. RAB5C belongs to the Ras-related protein family.

Ras-related protein Rab-33A is a protein that in humans is encoded by the RAB33A gene.

Ras-related protein Rab-27A is a protein that in humans is encoded by the RAB27A gene.

CAAX prenyl protease 2 is an enzyme that in humans is encoded by the RCE1 gene.

Ras-related protein Rab-26 is a protein that in humans is encoded by the RAB26 gene.

GTPase activating protein and VPS9 domains 1, also known as GAPVD1, Gapex-5 and RME-6 is a protein which in humans is encoded by the GAPVD1 gene.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000139998 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Pereira-Leal JB, Seabra MC (Nov 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID 11697911.
↑ "Entrez Gene: RAB15 RAB15, member RAS onocogene family".

Zuk PA, Elferink LA (1999). "Rab15 mediates an early endocytic event in Chinese hamster ovary cells". J. Biol. Chem. 274 (32): 22303–12. doi: 10.1074/jbc.274.32.22303 . PMID 10428799.
Zuk PA, Elferink LA (2000). "Rab15 differentially regulates early endocytic trafficking". J. Biol. Chem. 275 (35): 26754–64. doi: 10.1074/jbc.M000344200 . PMID 10837464.
Strick DJ, Francescutti DM, Zhao Y, Elferink LA (2002). "Mammalian suppressor of Sec4 modulates the inhibitory effect of Rab15 during early endocytosis". J. Biol. Chem. 277 (36): 32722–9. doi: 10.1074/jbc.M205101200 . PMID 12105226.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14". Nature. 421 (6923): 601–7. Bibcode:2003Natur.421..601H. doi: 10.1038/nature01348 . PMID 12508121.
Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi: 10.1074/jbc.M212341200 . PMID 12578829.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Strick DJ, Elferink LA (2006). "Rab15 effector protein: a novel protein for receptor recycling from the endocytic recycling compartment". Mol. Biol. Cell. 16 (12): 5699–709. doi:10.1091/mbc.E05-03-0204. PMC 1289414 . PMID 16195351.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000139998 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11697911-3] Pereira-Leal JB, Seabra MC (Nov 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID 11697911.

[entrez-4] "Entrez Gene: RAB15 RAB15, member RAS onocogene family".

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RAB15

Related Research Articles

References

Further reading