RAB33A

RAB33A
Identifiers
Aliases	RAB33A , RabS10, member RAS oncogene family
External IDs	OMIM: 300333; MGI: 109493; HomoloGene: 3522; GeneCards: RAB33A; OMA:RAB33A - orthologs
Gene location (Human) Chr. X chromosome (human) [1] Band Xq26.1 Start 130,171,962 bp [1] End 130,184,870 bp [1]
Gene location (Mouse) Chr. X chromosome (mouse) [2] Band X 25.68 cM|X A5 Start 48,519,285 bp [2] End 48,530,232 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in C1 segment prefrontal cortex gonad Brodmann area 9 middle frontal gyrus ganglionic eminence cerebellar hemisphere right hemisphere of cerebellum middle temporal gyrus right frontal lobe Top expressed in superior cervical ganglion barrel cortex facial motor nucleus medial geniculate nucleus anterior horn of spinal cord lateral geniculate nucleus saccule medial dorsal nucleus ganglionic eminence medial ganglionic eminence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GTP binding protein binding GTPase activity Cellular component plasma membrane membrane Golgi membrane endoplasmic reticulum membrane Biological process regulation of autophagosome assembly antigen processing and presentation intracellular protein transport endoplasmic reticulum to Golgi vesicle-mediated transport Rab protein signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9363 19337 Ensembl ENSG00000134594 ENSMUSG00000031104 UniProt Q14088 P97950 RefSeq (mRNA) NM_004794 NM_011228 RefSeq (protein) NP_004785 NP_035358 Location (UCSC) Chr X: 130.17 – 130.18 Mb Chr X: 48.52 – 48.53 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ras-related protein Rab-33A is a protein that in humans is encoded by the RAB33A gene. ^{[5] [6] [7]}

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is GTP-binding protein and may be involved in vesicle transport. ^[7]

References

1. GRCh38: Ensembl release 89: ENSG00000134594 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000031104 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Koda T, Kakinuma M (Sep 1993). "Molecular cloning of a cDNA encoding a novel small GTP-binding protein". FEBS Lett. 328 (1–2): 21–4. doi: 10.1016/0014-5793(93)80957-V . PMID   7688322.
6. Zheng JY, Koda T, Fujiwara T, Kishi M, Ikehara Y, Kakinuma M (Jul 1998). "A novel Rab GTPase, Rab33B, is ubiquitously expressed and localized to the medial Golgi cisternae". J Cell Sci. 111 (8): 1061–9. doi:10.1242/jcs.111.8.1061. PMID   9512502.
7. "Entrez Gene: RAB33A RAB33A, member RAS oncogene family".

Further reading

• Schimmöller F, Simon I, Pfeffer SR (1998). "Rab GTPases, directors of vesicle docking". J. Biol. Chem. 273 (35): 22161–4. doi: 10.1074/jbc.273.35.22161 . PMID   9712825.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC   2665286 . PMID   15772651.
• Jacobsen M, Repsilber D, Gutschmidt A, et al. (2005). "Ras-associated small GTPase 33A, a novel T cell factor, is down-regulated in patients with tuberculosis". J. Infect. Dis. 192 (7): 1211–8. doi: 10.1086/444428 . PMID   16136464.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.