RAB37

RAB37
Identifiers
Aliases	RAB37 , member RAS oncogene family
External IDs	OMIM: 609956 MGI: 1929945 HomoloGene: 23303 GeneCards: RAB37
Gene location (Human)
Chr.	Chromosome 17 (human)
End	74,747,335 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	115,053,062 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; monocyte; ; blood; ; spleen; ; bone marrow cells; ; right lobe of liver; ; endothelial cell; ; palpebral conjunctiva; ; pancreatic ductal cell; ; lymph node;
	Top expressed in
	islet of Langerhans; ; lateral geniculate nucleus; ; anterior horn of spinal cord; ; medial dorsal nucleus; ; medial geniculate nucleus; ; retinal pigment epithelium; ; cerebellar cortex; ; facial motor nucleus; ; blood; ; pontine nuclei;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding ; GTP binding ; protein binding ; GTPase activity ;
Cellular component	cytoplasmic vesicle ; endoplasmic reticulum-Golgi intermediate compartment ; azurophil granule membrane ; specific granule membrane ; endosome ; plasma membrane ; synaptic vesicle ; secretory granule membrane ; intracellular anatomical structure ;
Biological process	protein transport ; neutrophil degranulation ; vesicle docking involved in exocytosis ; protein secretion ; protein localization to plasma membrane ; regulation of exocytosis ; intracellular protein transport ; Rab protein signal transduction ; small GTPase mediated signal transduction ;
	Sources:Amigo / QuickGO
Orthologs
	326624
	58222
	ENSG00000172794
	ENSMUSG00000020732
	Q96AX2
	Q9JKM7
NM_001006637 ; NM_001006638 ; NM_001163989 ; NM_001163990 ; NM_175738 ;
	NM_001330471
	NM_001163753 ; NM_021411
	NP_001006639 ; NP_001157461 ; NP_001157462 ; NP_001317400 ; NP_783865
	NP_001157225 ; NP_067386
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 14, 2022

Ras-related protein Rab-37 is a protein that in humans is encoded by the RAB37 gene.^[5]^[6]

Rab proteins are low molecular mass GTPases that are critical regulators of vesicle trafficking. For additional background information on Rab proteins, see MIM 179508.[supplied by OMIM]^[6]

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Ras-related protein Rab-22A is a protein that in humans is encoded by the RAB22A gene.

Ras-related protein Rab-3D is a protein that in humans is encoded by the RAB3D gene.

Cdc42 effector protein 1 is a protein that in humans is encoded by the CDC42EP1 gene.

GTP-binding protein GEM is a protein that in humans is encoded by the GEM gene.

ADP-ribosylation factor-related protein 1 is a protein that in humans is encoded by the ARFRP1 gene.

RalBP1-associated Eps domain-containing protein 1 is a protein that in humans is encoded by the REPS1 gene.

RAB3A-interacting protein is a protein that in humans is encoded by the RAB3IP gene.

Ras-related protein Rab-40A is a protein that in humans is encoded by the RAB40A gene.

Transcription factor RFX3 is a protein that in humans is encoded by the RFX3 gene.

Ras-related protein Rab-15 is a protein that in humans is encoded by the RAB15 gene.

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Ras-related protein Rab-33A is a protein that in humans is encoded by the RAB33A gene.

Rab9 effector protein with Kelch motifs also known as p40 is a protein that in humans is encoded by the RABEPK gene.

Rhophilin-1 is a protein that in humans is encoded by the RHPN1 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000172794 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020732 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Masuda ES, Luo Y, Young C, Shen M, Rossi AB, Huang BC, Yu S, Bennett MK, Payan DG, Scheller RH (May 2000). "Rab37 is a novel mast cell specific GTPase localized to secretory granules". FEBS Lett. 470 (1): 61–4. doi:10.1016/S0014-5793(00)01288-6. PMID 10722846. S2CID 38218555.
1 2 "Entrez Gene: RAB37 RAB37, member RAS oncogene family".

Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Breuza L, Halbeisen R, Jenö P, et al. (2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46". J. Biol. Chem. 279 (45): 47242–53. doi: 10.1074/jbc.M406644200 . PMID 15308636.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801. S2CID 23783563.
Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi: 10.1074/jbc.M212341200 . PMID 12578829.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000172794 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020732 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10722846-5] Masuda ES, Luo Y, Young C, Shen M, Rossi AB, Huang BC, Yu S, Bennett MK, Payan DG, Scheller RH (May 2000). "Rab37 is a novel mast cell specific GTPase localized to secretory granules". FEBS Lett. 470 (1): 61–4. doi:10.1016/S0014-5793(00)01288-6. PMID 10722846. S2CID 38218555.

[entrez-6] 1 2 "Entrez Gene: RAB37 RAB37, member RAS oncogene family".

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RAB37

Related Research Articles

References

Further reading