RAB39B

RAB39B
Identifiers
Aliases	RAB39B , MRX72, WSMN, member RAS oncogene family, BGMR, WSN, XLID72
External IDs	OMIM: 300774; MGI: 1915040; HomoloGene: 62377; GeneCards: RAB39B; OMA:RAB39B - orthologs
Gene location (Human) Chr. X chromosome (human) [1] Band Xq28 Start 155,258,235 bp [1] End 155,264,491 bp [1]
Gene location (Mouse) Chr. X chromosome (mouse) [2] Band X 38.26 cM|X A7.3 Start 74,615,652 bp [2] End 74,621,837 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell Brodmann area 23 middle temporal gyrus primary visual cortex islet of Langerhans Brodmann area 46 prefrontal cortex dorsolateral prefrontal cortex Brodmann area 9 superior frontal gyrus Top expressed in supraoptic nucleus superior cervical ganglion primary motor cortex facial motor nucleus ventromedial nucleus substantia nigra lateral hypothalamus piriform cortex trigeminal ganglion mammillary body More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GTP binding myosin V binding protein binding GTPase activity Cellular component neuron projection vesicle plasma membrane intracellular anatomical structure membrane Golgi apparatus cytoplasmic vesicle membrane cytoplasmic vesicle Biological process protein transport synapse organization vesicle-mediated transport regulation of autophagy autophagy intracellular protein transport Rab protein signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 116442 67790 Ensembl ENSG00000155961 ENSMUSG00000031202 UniProt Q96DA2 Q8BHC1 RefSeq (mRNA) NM_171998 NM_175122 RefSeq (protein) NP_741995 NP_780331 Location (UCSC) Chr X: 155.26 – 155.26 Mb Chr X: 74.62 – 74.62 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ras-related protein Rab-39B is a protein that in humans is encoded by the RAB39B gene. ^{[5] [6]}

This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking. ^[6]

References

1. GRCh38: Ensembl release 89: ENSG00000155961 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000031202 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Cheng H, Ma Y, Ni X, Jiang M, Guo L, Ying K, Xie Y, Mao Y (Nov 2002). "Isolation and characterization of a human novel RAB (RAB39B) gene". Cytogenet Genome Res. 97 (1–2): 72–5. doi:10.1159/000064047. PMID   12438742. S2CID   26566228.
6. "Entrez Gene: RAB39B RAB39B, member RAS oncogene family".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC   2665286 . PMID   15772651.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.