RASSF8

RASSF8
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CS4
Identifiers
Aliases	RASSF8 , C12orf2, HOJ1, Ras association domain family member 8
External IDs	OMIM: 608231; MGI: 1918573; HomoloGene: 5219; GeneCards: RASSF8; OMA:RASSF8 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12p12.1 Start 25,959,029 bp [1] End 26,079,892 bp [1]
Gene location (Mouse) Chr. Chromosome 6 (mouse) [2] Band 6|6 G3 Start 145,692,474 bp [2] End 145,766,805 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm Achilles tendon stromal cell of endometrium left testis right testis retinal pigment epithelium epithelium of colon sural nerve Skeletal muscle tissue of rectus abdominis secondary oocyte Top expressed in gastrula ciliary body iris decidua pineal gland vas deferens Epithelium of choroid plexus neural layer of retina stria vascularis efferent ductule More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 11228 71323 Ensembl ENSG00000123094 ENSMUSG00000030259 UniProt Q8NHQ8 Q8CJ96 RefSeq (mRNA) NM_001164746 NM_001164747 NM_001164748 NM_007211 NM_027760 RefSeq (protein) NP_001158218 NP_001158219 NP_001158220 NP_009142 NP_082036 Location (UCSC) Chr 12: 25.96 – 26.08 Mb Chr 6: 145.69 – 145.77 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ras association domain-containing protein 8 is a protein that in humans is encoded by the RASSF8 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000123094 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030259 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: RASSF8 Ras association (RalGDS/AF-6) domain family 8".

Further reading

• Falvella FS, Spinola M, Manenti G, et al. (2007). "Common polymorphisms in D12S1034 flanking genes RASSF8 and BHLHB3 are not associated with lung adenocarcinoma risk". Lung Cancer. 56 (1): 1–7. doi:10.1016/j.lungcan.2006.11.008. PMID   17194498.
• Falvella FS, Manenti G, Spinola M, et al. (2006). "Identification of RASSF8 as a candidate lung tumor suppressor gene". Oncogene. 25 (28): 3934–3938. doi: 10.1038/sj.onc.1209422 . PMID   16462760.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–1178. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–1450. Bibcode:2004CBio...14.1436J. doi: 10.1016/j.cub.2004.07.051 . PMID   15324660.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Debeer P, Schoenmakers EF, Twal WO, et al. (2002). "The fibulin-1 gene (FBLN1) is disrupted in a t(12;22) associated with a complex type of synpolydactyly". J. Med. Genet. 39 (2): 98–104. doi:10.1136/jmg.39.2.98. PMC   1735038 . PMID   11836357.
• Debeer P, Schoenmakers EF, Thoelen R, et al. (2000). "Physical map of a 1.5 mb region on 12p11.2 harbouring a synpolydactyly associated chromosomal breakpoint". Eur. J. Hum. Genet. 8 (8): 561–570. doi: 10.1038/sj.ejhg.5200497 . PMID   10951517.