RERG

RERG
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2ATV
Identifiers
Aliases	RERG , RAS like estrogen regulated growth inhibitor
External IDs	OMIM: 612664; MGI: 2665139; HomoloGene: 50026; GeneCards: RERG; OMA:RERG - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12p12.3 Start 15,107,783 bp [1] End 15,348,675 bp [1]
Gene location (Mouse) Chr. Chromosome 6 (mouse) [2] Band 6|6 G1 Start 137,031,823 bp [2] End 137,147,495 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in germinal epithelium tail of epididymis body of uterus synovial joint Achilles tendon left uterine tube caput epididymis myometrium saphenous vein synovial membrane Top expressed in adrenal gland facial motor nucleus umbilical cord molar lumbar subsegment of spinal cord dentate gyrus of hippocampal formation granule cell body of femur calvaria conjunctival fornix left lung lobe More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding GTP binding GDP binding estrogen receptor binding GTPase activity Cellular component cytosol nucleus membrane cytoplasm plasma membrane Biological process negative regulation of cell population proliferation response to hormone negative regulation of cell growth signal transduction small GTPase mediated signal transduction Ras protein signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 85004 232441 Ensembl ENSG00000134533 ENSMUSG00000030222 UniProt Q96A58 Q8R367 RefSeq (mRNA) NM_001190726 NM_032918 NM_001164212 NM_001164214 NM_181988 RefSeq (protein) NP_001177655 NP_116307 NP_001157684 NP_001157686 NP_871788 Location (UCSC) Chr 12: 15.11 – 15.35 Mb Chr 6: 137.03 – 137.15 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RAS-like, estrogen-regulated, growth inhibitor is a protein in humans that is encoded by the RERG gene. ^[5]

RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009].

References

1. GRCh38: Ensembl release 89: ENSG00000134533 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030222 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: RAS-like, estrogen-regulated, growth inhibitor" . Retrieved 2012-11-09.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Ras-related and estrogen-regulated growth inhibitor (RERG)