RHPN1

RHPN1
Identifiers
Aliases	RHPN1 , ODF5, RHOPHILIN, RHPN, rhophilin, Rho GTPase binding protein 1, rhophilin Rho GTPase binding protein 1
External IDs	OMIM: 601031 MGI: 1098783 HomoloGene: 7346 GeneCards: RHPN1
Gene location (Human)
Chr.	Chromosome 8 (human)
End	143,384,221 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	75,587,334 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; left lobe of thyroid gland; ; anterior pituitary; ; right uterine tube; ; nucleus accumbens; ; Brodmann area 9; ; amygdala; ; cingulate gyrus; ; caudate nucleus; ; hypothalamus;
	Top expressed in
	saccule; ; spermatocyte; ; spermatid; ; otic placode; ; proximal tubule; ; renal corpuscle; ; superior frontal gyrus; ; yolk sac; ; renal calyx; ; seminiferous tubule;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding ;
Cellular component	cytosol ;
Biological process	signal transduction ;
	Sources:Amigo / QuickGO
Orthologs
	114822
	14787
	ENSG00000158106
	ENSMUSG00000022580
	Q8TCX5
	Q61085
	NM_052924
	NM_001163465 ; NM_008164
	NP_443156
	NP_001156937 ; NP_032190
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 17, 2022

Rhophilin-1 is a protein that in humans is encoded by the RHPN1 gene.^[5]^[6]

Related Research Articles

Nuclear autoantigenic sperm protein is a protein that in humans is encoded by the NASP gene. Multiple isoforms are encoded by transcript variants of this gene.

Cdc42 effector protein 3 is a protein that in humans is encoded by the CDC42EP3 gene.

Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene. The cold inducible RNA-binding protein CIRBP plays a critical role in controlling the cellular response upon confronting a variety of cellular stresses, including short wavelength ultraviolet light, hypoxia, and hypothermia.

Cdc42 effector protein 1 is a protein that in humans is encoded by the CDC42EP1 gene.

GTP-binding protein GEM is a protein that in humans is encoded by the GEM gene.

CD2 antigen cytoplasmic tail-binding protein 2 is a protein that in humans is encoded by the CD2BP2 gene.

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 is a protein that in humans is encoded by the GNG11 gene.

DNA-binding protein RFX2 is a protein that in humans is encoded by the RFX2 gene.

Calmegin, also known as CLGN, is a protein which in humans is encoded by the CLGN gene. Calmegin is also present in other animals including mice.

SH3 domain-binding protein 1 is a protein that in humans is encoded by the SH3BP1 gene.

Cdc42 effector protein 4 is a protein that in humans is encoded by the CDC42EP4 gene.

Syntenin-2 is a protein that in humans is encoded by the SDCBP2 gene.

Transcription factor RFX3 is a protein that in humans is encoded by the RFX3 gene.

Synaptotagmin-4 is a protein that in humans is encoded by the SYT4 gene.

Copine-1 is a protein that in humans is encoded by the CPNE1 gene.

Zinc finger and BTB domain-containing protein 7B is a protein that in humans is encoded by the ZBTB7B gene. ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes and has a role in development.[supplied by OMIM]

Ras-related protein Rab-33A is a protein that in humans is encoded by the RAB33A gene.

Sperm flagellar protein 1 is a protein that in humans is encoded by the SPEF1 gene.

Transcription initiation factor TFIID subunit 9B is a protein that in humans is encoded by the TAF9B gene.

THAP domain-containing protein 7 is a protein that in humans is encoded by the THAP7 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000158106 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022580 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Nagase T, Kikuno R, Ohara O (Sep 2001). "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins". DNA Res. 8 (4): 179–87. doi: 10.1093/dnares/8.4.179 . PMID 11572484.
↑ "Entrez Gene: RHPN1 rhophilin, Rho GTPase binding protein 1".

Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Jaffe AB, Aspenström P, Hall A (2004). "Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways". Mol. Cell. Biol. 24 (4): 1736–46. doi:10.1128/MCB.24.4.1736-1746.2004. PMC 344169 . PMID 14749388.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Peck JW, Oberst M, Bouker KB, et al. (2003). "The RhoA-binding protein, rhophilin-2, regulates actin cytoskeleton organization". J. Biol. Chem. 277 (46): 43924–32. doi: 10.1074/jbc.M203569200 . PMID 12221077.
Fujita A, Nakamura K, Kato T, et al. (2000). "Ropporin, a sperm-specific binding protein of rhophilin, that is localized in the fibrous sheath of sperm flagella". J. Cell Sci. 113 (1): 103–12. doi:10.1242/jcs.113.1.103. hdl: 2433/181273 . PMID 10591629.

This protein-related article is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000158106 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022580 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11572484-5] Nagase T, Kikuno R, Ohara O (Sep 2001). "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins". DNA Res. 8 (4): 179–87. doi: 10.1093/dnares/8.4.179 . PMID 11572484.

[entrez-6] "Entrez Gene: RHPN1 rhophilin, Rho GTPase binding protein 1".

[1]

[2]

[3]

[4]

[5]

[6]

RHPN1

Related Research Articles

References

Further reading