RNF122

RNF122
Identifiers
Aliases	RNF122 , ring finger protein 122
External IDs	MGI: 1916117; HomoloGene: 11717; GeneCards: RNF122; OMA:RNF122 - orthologs
Gene location (Human) Chr. Chromosome 8 (human) [1] Band 8p12 Start 33,547,754 bp [1] End 33,567,128 bp [1]
Gene location (Mouse) Chr. Chromosome 8 (mouse) [2] Band 8|8 A3 Start 31,601,848 bp [2] End 31,621,510 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left uterine tube right ovary left ovary muscle of thigh ganglionic eminence right auricle of heart gastrocnemius muscle right uterine tube granulocyte upper lobe of left lung Top expressed in zygote hand Rostral migratory stream maxillary prominence mandibular prominence primary oocyte genital tubercle superior cervical ganglion secondary oocyte ganglionic eminence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function ubiquitin protein ligase activity metal ion binding protein binding Cellular component integral component of membrane Golgi apparatus membrane endoplasmic reticulum endomembrane system cytoplasm Biological process proteasome-mediated ubiquitin-dependent protein catabolic process protein polyubiquitination protein ubiquitination negative regulation of mitochondrial membrane potential positive regulation of apoptotic process protein autoubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79845 68867 Ensembl ENSG00000133874 ENSMUSG00000039328 UniProt Q9H9V4 Q8BP31 RefSeq (mRNA) NM_024787 NM_175136 NM_001368373 NM_001368374 NM_001368375 RefSeq (protein) NP_079063 NP_780345 NP_001355302 NP_001355303 NP_001355304 Location (UCSC) Chr 8: 33.55 – 33.57 Mb Chr 8: 31.6 – 31.62 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RING finger protein 122 is a protein that in humans is encoded by the RNF122 gene. ^[5]

The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000133874 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000039328 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: RNF122 ring finger protein 122".

Further reading

• Koyama K, Sudo K, Nakamura Y (1995). "Isolation of 115 human chromosome 8-specific expressed-sequence tags by exon amplification". Genomics. 26 (2): 245–53. doi:10.1016/0888-7543(95)80207-3. PMID   7601449.
• Saurin AJ, Borden KL, Boddy MN, Freemont PS (1996). "Does this have a familiar RING?". Trends Biochem. Sci. 21 (6): 208–14. doi:10.1016/s0968-0004(96)80017-x. PMID   8744354.
• Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. Bibcode:2000PNAS...97.3491D. doi: 10.1073/pnas.97.7.3491 . PMC   16267 . PMID   10737800.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Wang L, Gao X, Gao P, et al. (2006). "Cell-based screening and validation of human novel genes associated with cell viability". Journal of Biomolecular Screening. 11 (4): 369–76. doi: 10.1177/1087057106286654 . PMID   16751333.
• Wang L, Shi TP, Wang L, et al. (2006). "[Cloning, expression and subcellular localization of a novel human gene-RNF122]". Beijing da Xue Xue Bao. 38 (3): 239–43. PMID   16778963.