RNF26

RNF26
Identifiers
Aliases	RNF26 , ring finger protein 26
External IDs	OMIM: 606130 MGI: 2388131 HomoloGene: 12924 GeneCards: RNF26
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q23.3 Start 119,334,527 bp [1] End 119,337,309 bp [1]
Gene ontology Molecular function • metal ion binding • GO:0001948 protein binding • zinc ion binding • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • transferase activity Cellular component • integral component of membrane • membrane • endoplasmic reticulum • endoplasmic reticulum membrane Biological process • endosome organization • regulation of type I interferon production • negative regulation of defense response to virus • protein K11-linked ubiquitination • protein localization to perinuclear region of cytoplasm • protein ubiquitination Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	79102	213211
Ensembl	ENSG00000173456	ENSMUSG00000053128
UniProt	Q9BY78	Q8BUH7
RefSeq (mRNA)	NM_032015	NM_153762
RefSeq (protein)	NP_114404	NP_717095
Location (UCSC)	Chr 11: 119.33 – 119.34 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Ring finger protein 26 is a protein that in humans is encoded by the RNF26 gene. ^[4]

Function

The protein encoded by this intronless gene contains a C3HC5 type of RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The expression of this gene was found to be upregulated in cancer cell lines derived from different types of cancer. [provided by RefSeq, Jul 2008].

References

1. GRCh38: Ensembl release 89: ENSG00000173456 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: Ring finger protein 26" . Retrieved 2013-07-15.

Further reading

• Katoh M (April 2001). "Molecular cloning and characterization of RNF26 on human chromosome 11q23 region, encoding a novel RING finger protein with leucine zipper". Biochemical and Biophysical Research Communications. 282 (4): 1038–44. doi:10.1006/bbrc.2001.4671. PMID   11352657.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.