RPAIN

RPAIN
Identifiers
Aliases	RPAIN , HRIP, RIP, RPA interacting protein
External IDs	OMIM: 617299; MGI: 1916973; HomoloGene: 13006; GeneCards: RPAIN; OMA:RPAIN - orthologs
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17p13.2 Start 5,419,641 bp [1] End 5,432,877 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11|11 B4 Start 70,861,039 bp [2] End 70,868,659 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence middle temporal gyrus anterior pituitary ventricular zone sperm left ovary Brodmann area 23 right ovary muscle of thigh gastrocnemius muscle Top expressed in spermatid spermatocyte right kidney yolk sac lens neural layer of retina parotid gland ascending aorta neural tube aortic valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding protein-containing complex binding Cellular component cytoplasm PML body nucleus fibrillar center Biological process DNA-dependent DNA replication DNA recombination response to UV DNA repair protein import into nucleus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84268 69723 Ensembl ENSG00000129197 ENSMUSG00000018449 UniProt Q86UA6 Q9CWY9 RefSeq (mRNA) NM_001033002 NM_001160243 NM_001160244 NM_001160246 NM_001160266 NM_001160267 NM_032308 NM_001252413 NM_001252414 NM_001252415 NM_027186 RefSeq (protein) NP_001028174 NP_001153715 NP_001153716 NP_001153718 NP_001153738 NP_001239342 NP_001239343 NP_001239344 NP_081462 Location (UCSC) Chr 17: 5.42 – 5.43 Mb Chr 11: 70.86 – 70.87 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RPA-interacting protein is a protein that in humans is encoded by the RPAIN gene. ^{[5] [6] [7]}

See also

• Replication protein A (RPA)

References

1. GRCh38: Ensembl release 89: ENSG00000129197 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000018449 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Park J, Seo T, Kim H, Choe J (Sep 2005). "Sumoylation of the novel protein hRIP{beta} is involved in replication protein A deposition in PML nuclear bodies". Mol Cell Biol. 25 (18): 8202–14. doi:10.1128/MCB.25.18.8202-8214.2005. PMC   1234305 . PMID   16135809.
6. Chen JZ, Huang SD, Ji CN, Pang RY, Xie Y, Xue JL (Jul 2005). "Identification, expression pattern, and subcellular location of human RIP isoforms". DNA Cell Biol. 24 (7): 464–9. doi:10.1089/dna.2005.24.464. PMID   16008515.
7. "Entrez Gene: RPAIN RPA interacting protein".

Further reading

• Blonska M, You Y, Geleziunas R, Lin X (2004). "Restoration of NF-kappaB activation by tumor necrosis factor alpha receptor complex-targeted MEKK3 in receptor-interacting protein-deficient cells". Mol. Cell. Biol. 24 (24): 10757–65. doi:10.1128/MCB.24.24.10757-10765.2004. PMC   533972 . PMID   15572679.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.