RRS1

RRS1
Identifiers
Aliases	RRS1 , ribosome biogenesis regulator homolog, ribosome biogenesis regulator 1 homolog
External IDs	OMIM: 618311; MGI: 1929721; HomoloGene: 41014; GeneCards: RRS1; OMA:RRS1 - orthologs
Gene location (Human) Chr. Chromosome 8 (human) [1] Band 8q13.1 Start 66,429,014 bp [1] End 66,430,733 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1 A2|1 2.08 cM Start 9,615,633 bp [2] End 9,617,680 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle synovial membrane body of pancreas skeletal muscle tissue muscle of thigh mucosa of transverse colon monocyte left uterine tube body of stomach left ventricle Top expressed in epiblast otic vesicle cingulate gyrus upper arm mesenchyme epithelium of small intestine autopod region intestinal villus amygdala embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding RNA binding 5S rRNA binding Cellular component condensed nuclear chromosome nucleolus nucleus endoplasmic reticulum preribosome, large subunit precursor fibrillar center Biological process ribosomal large subunit export from nucleus mitotic metaphase plate congression ribosome biogenesis hematopoietic progenitor cell differentiation endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal large subunit assembly ribosomal large subunit biogenesis protein localization to nucleolus regulation of signal transduction by p53 class mediator Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23212 59014 Ensembl ENSG00000179041 ENSMUSG00000061024 UniProt Q15050 Q9CYH6 RefSeq (mRNA) NM_015169 NM_021511 RefSeq (protein) NP_055984 NP_067486 Location (UCSC) Chr 8: 66.43 – 66.43 Mb Chr 1: 9.62 – 9.62 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ribosome biogenesis regulatory protein homolog is a protein that in humans is encoded by the RRS1 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000179041 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000061024 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S, Ishikawa K, Kawarabayasi Y, Kotani H, et al. (Jul 1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (1): 37–43. doi: 10.1093/dnares/2.1.37 . PMID   7788527.
6. Tsuno A, Miyoshi K, Tsujii R, Miyakawa T, Mizuta K (Mar 2000). "RRS1, a Conserved Essential Gene, Encodes a Novel Regulatory Protein Required for Ribosome Biogenesis in Saccharomyces cerevisiae". Mol Cell Biol. 20 (6): 2066–74. doi:10.1128/MCB.20.6.2066-2074.2000. PMC   110823 . PMID   10688653.
7. "Entrez Gene: RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)".

Further reading

• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID   15635413. S2CID   4344740.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC   133617 . PMID   12429849.
• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi: 10.1016/S0960-9822(01)00650-9 . PMID   11790298. S2CID   14132033.