RTFDC1

RTF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2BZE, 2DB9, 3U1U, 4L1P, 4L1U
Identifiers
Aliases	15890 RTF1, RTF2 , GTL7, KIAA0252, RTF1 homolog, Paf1/RNA polymerase II complex component, RTF2, C20orf43, CDAO5, HSPC164, SHUJUN-3, replication termination factor 2 domain containing 1, replication termination factor 2, RTFDC1
External IDs	OMIM: 611633 MGI: 1309480 HomoloGene: 133868 9501 GeneCards: RTF2 RTF1, RTF2
Gene location (Human) Chr. Chromosome 15 (human) [1] Band 15q15.1, 20q13.31 Start 41,408,408 bp [1] End 41,483,563 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 E5 Start 119,675,068 bp [2] End 119,735,407 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence palpebral conjunctiva bone marrow cells cerebellar hemisphere body of tongue ganglionic eminence palpebral conjunctiva bone marrow cells cerebellar hemisphere body of tongue monocyte caput epididymis saphenous vein human penis urinary bladder Achilles tendon monocyte popliteal artery gastrocnemius muscle ganglionic eminence prefrontal cortex caudate nucleus ascending aorta left coronary artery right coronary artery Top expressed in hand yolk sac superior cervical ganglion foot interventricular septum primitive streak fossa condyle trigeminal ganglion ganglionic eminence More reference expression data BioGPS 51507/ More reference expression data
Gene ontology Molecular function protein binding single-stranded DNA binding DNA binding RNA polymerase II C-terminal domain phosphoserine binding RNA binding molecular function Cellular component nucleolus nucleus Cdc73/Paf1 complex nucleoplasm cellular component replication fork chromosome Biological process blastocyst growth histone modification regulation of transcription, DNA-templated positive regulation of transcription elongation from RNA polymerase II promoter histone H3-K4 trimethylation positive regulation of histone H3-K4 methylation transcription, DNA-templated Wnt signaling pathway positive regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II stem cell population maintenance endodermal cell fate commitment transcription by RNA polymerase II transcription elongation from RNA polymerase II promoter protein ubiquitination mitotic DNA replication termination site-specific DNA replication termination at RTS1 barrier biological process cellular response to hydroxyurea regulation of DNA stability Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23168,51507 23168,51507 76246 Ensembl ENSG00000137815 ENSG00000022277 ENSMUSG00000027304 UniProt Q92541 Q9BY42 A2AQ19 RefSeq (mRNA) NM_015138 NM_001283035 NM_001283036 NM_001283037 NM_016407 NM_030112 RefSeq (protein) NP_055953 NP_001269964 NP_001269965 NP_001269966 NP_057491 NP_084388 Location (UCSC) Chr 15: 41.41 – 41.48 Mb Chr 2: 119.68 – 119.74 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Replication termination factor 2 is a protein that in humans is encoded by the RTF2 gene. ^[5]

References

1. ENSG00000022277 GRCh38: Ensembl release 89: ENSG00000137815, ENSG00000022277 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000027304 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "RTF2 replication termination factor 2 [ Homo sapiens (human) ]".

External links

• Human RTFDC1 genome location and RTFDC1 gene details page in the UCSC Genome Browser .

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi: 10.1073/pnas.160270997 . PMC   16901 . PMID   10931946.
• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC   310934 . PMID   11042152.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi: 10.1038/414865a . PMID   11780052.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID   15635413. S2CID   4344740.