RTN3 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | RTN3 , ASYIP, HAP, NSPL2, NSPLII, RTN3-A1, reticulon 3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 604249 MGI: 1339970 HomoloGene: 24934 GeneCards: RTN3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Reticulon-3 is a protein that in humans is encoded by the RTN3 gene. [5] [6]
The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues (see, e.g., RTN1; MIM 600865).[supplied by OMIM] [6]
p73 is a protein related to the p53 tumor protein. Because of its structural resemblance to p53, it has also been considered a tumor suppressor. It is involved in cell cycle regulation, and induction of apoptosis. Like p53, p73 is characterized by the presence of different isoforms of the protein. This is explained by splice variants, and an alternative promoter in the DNA sequence.
The activin A receptor also known as ACVR1C or ALK-7 is a protein that in humans is encoded by the ACVR1C gene. ACVR1C is a type I receptor for the TGFB family of signaling molecules.
Radiation-inducible immediate-early gene IEX-1 is a protein that in humans is encoded by the IER3 gene.
Sphingosine-1-phosphate receptor 2, also known as S1PR2 or S1P2, is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P).
Reticulon 4, also known as Neurite outgrowth inhibitor or Nogo, is a protein that in humans is encoded by the RTN4 gene that has been identified as an inhibitor of neurite outgrowth specific to the central nervous system. During neural development Nogo is expressed mainly by neurons and provides an inhibitory signal for the migration and sprouting of CNS endothelial (tip) cells, thereby restricting blood vessel density.
Calpastatin is a protein that in humans is encoded by the CAST gene.
Hematopoietic lineage cell-specific protein is a protein that in humans is encoded by the HCLS1 gene.
FAS-associated factor 1 is a protein that in humans is encoded by the FAF1 gene.
Reticulon-1 also known as neuroendocrine-specific protein (NSP) is a protein that in humans is encoded by the RTN1 gene.
Baculoviral IAP repeat-containing protein 1 is a protein that in humans is encoded by the NAIP gene.
Ceramide glucosyltransferase is an enzyme that in humans is encoded by the UGCG gene.
CDK5 regulatory subunit-associated protein 3 is a protein that in humans is encoded by the CDK5RAP3 gene.
Tubulin alpha-1C chain is a protein that in humans is encoded by the TUBA1C gene.
DnaJ homolog subfamily B member 11 is a protein that in humans is encoded by the DNAJB11 gene.
Protein arginine N-methyltransferase 2 is an enzyme that in humans is encoded by the PRMT2 gene.
39S ribosomal protein L41, mitochondrial is a protein that in humans is encoded by the MRPL41 gene.
Tumor protein p53-inducible protein 11 is a protein that in humans is encoded by the TP53I11 gene.
Cell death-inducing DFFA-like effector b, also known as CIDEB, is a human gene.
Reticulon-2 is a protein that in humans is encoded by the RTN2 gene.
ADP/ATP translocase 3, also known as solute carrier family 25 member 6, is a protein that in humans is encoded by the SLC25A6 gene.