Redox-regulatory protein FAM213A

PRXL2A
Identifiers
Aliases	PRXL2A , C10orf58, PAMM, family with sequence similarity 213 member A, Adrx, FAM213A, peroxiredoxin like 2A
External IDs	OMIM: 617165 MGI: 1917814 HomoloGene: 12356 GeneCards: PRXL2A
Gene location (Human) Chr. Chromosome 10 (human) [1] Band 10q23.1 Start 80,407,829 bp [1] End 80,437,115 bp [1]
Gene location (Mouse) Chr. Chromosome 14 (mouse) [2] Band 14|14 B Start 40,715,697 bp [2] End 40,735,745 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in retinal pigment epithelium corpus epididymis jejunal mucosa caput epididymis vulva postcentral gyrus adipose tissue subcutaneous adipose tissue superior frontal gyrus pons Top expressed in retinal pigment epithelium blood utricle ciliary body brown adipose tissue white adipose tissue dorsomedial hypothalamic nucleus supraoptic nucleus subcutaneous adipose tissue parotid gland More reference expression data BioGPS n/a
Gene ontology Molecular function antioxidant activity Cellular component cytoplasm extracellular region Biological process regulation of osteoclast differentiation cellular oxidant detoxification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84293 70564 Ensembl ENSG00000122378 ENSMUSG00000021792 UniProt Q9BRX8 Q9CYH2 RefSeq (mRNA) NM_001243778 NM_001243779 NM_001243780 NM_001243781 NM_001243782 NM_032333 NM_027464 NM_001316732 NM_001316733 NM_001316734 NM_001316735 NM_001316736 NM_001316737 NM_001316739 NM_001316740 NM_001378813 NM_001378814 NM_001378815 RefSeq (protein) NP_001230707 NP_001230708 NP_001230709 NP_001230710 NP_001230711 NP_115709 NP_001303661 NP_001303662 NP_001303663 NP_001303664 NP_001303665 NP_001303666 NP_001303668 NP_001303669 NP_081740 NP_001365742 NP_001365743 NP_001365744 Location (UCSC) Chr 10: 80.41 – 80.44 Mb Chr 14: 40.72 – 40.74 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Redox-regulatory protein FAM213A also known as peroxiredoxin-like 2 activated in M-CSF stimulated monocytes (PAMM) is a protein that in humans is encoded by the FAM213A gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000122378 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021792 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Yu Y, Zhang C, Zhou G, Wu S, Qu X, Wei H, Xing G, Dong C, Zhai Y, Wan J, Ouyang S, Li L, Zhang S, Zhou K, Zhang Y, Wu C, He F (Aug 2001). "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs". Genome Res. 11 (8): 1392–1403. doi:10.1101/gr.175501. PMC   311073 . PMID   11483580.
6. "Entrez Gene: C10orf58 chromosome 10 open reading frame 58".

Further reading

• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–126. doi: 10.1093/dnares/12.2.117 . PMID   16303743.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–2270. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.