Ribosome biogenesis protein BRX1 homolog

BRIX1
Identifiers
Aliases	BRIX1 , BRIX, BXDC2, BRX1, biogenesis of ribosomes, biogenesis of ribosomes BRX1
External IDs	OMIM: 618466 MGI: 1915082 HomoloGene: 10133 GeneCards: BRIX1
Gene location (Human) Chr. Chromosome 5 (human) [1] Band 5p13.2 Start 34,915,677 bp [1] End 34,925,996 bp [1]
Gene location (Mouse) Chr. Chromosome 15 (mouse) [2] Band 15|15 A1 Start 10,474,865 bp [2] End 10,486,033 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon ganglionic eminence islet of Langerhans rectum left uterine tube left coronary artery canal of the cervix tibial nerve skin of abdomen monocyte Top expressed in secondary oocyte morula primitive streak otic placode hair follicle abdominal wall maxillary prominence somite Paneth cell condyle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA binding protein binding Cellular component nucleolus nucleus Biological process ribosome biogenesis ribosomal large subunit assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55299 67832 Ensembl ENSG00000113460 ENSMUSG00000022247 UniProt Q8TDN6 Q9DCA5 RefSeq (mRNA) NM_018321 NM_026396 RefSeq (protein) NP_060791 NP_080672 Location (UCSC) Chr 5: 34.92 – 34.93 Mb Chr 15: 10.47 – 10.49 Mb PubMed search [3] [4]
Wikidata
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Ribosome biogenesis protein BRX1 homolog (BRIX1) also known as brix domain-containing protein 2 (BXDC2) is a protein that in humans is encoded by the BRIX1 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000113460 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000022247 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
6. "Entrez Gene: BXDC2 brix domain containing 2".

Further reading

• Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi: 10.1016/S0960-9822(01)00650-9 . PMID   11790298. S2CID   14132033.
• Kaser A, Bogengruber E, Hallegger M, Doppler E, Lepperdinger G, Jantsch M, et al. (2002). "Brix from xenopus laevis and brx1p from yeast define a new family of proteins involved in the biogenesis of large ribosomal subunits". Biol. Chem. 382 (12): 1637–47. doi:10.1515/BC.2001.199. PMID   11843177. S2CID   23636837.
• Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.