SARNP

SARNP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DO1
Identifiers
Aliases	SARNP , CIP29, HCC1, HSPC316, THO1, SAP domain containing ribonucleoprotein
External IDs	OMIM: 610049; MGI: 1913368; HomoloGene: 41628; GeneCards: SARNP; OMA:SARNP - orthologs
Gene location (Mouse) Chr. Chromosome 10 (mouse) [1] Band 10|10 D3 Start 128,817,333 bp [1] End 128,877,629 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence smooth muscle tissue Achilles tendon monocyte tibial nerve right adrenal gland ascending aorta islet of Langerhans gastrocnemius muscle left coronary artery Top expressed in ventricular zone ganglionic eminence epiblast lens neural tube yolk sac ovary thymus embryo embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding protein binding RNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific protein C-terminus binding RS domain binding Cellular component nuclear speck transcription export complex nucleus nucleoplasm cytoplasmic ribonucleoprotein granule Biological process mRNA transport regulation of transcription, DNA-templated regulation of translation transcription, DNA-templated RNA export from nucleus mRNA export from nucleus termination of RNA polymerase II transcription mRNA 3'-end processing transport negative regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84324 66118 Ensembl n/a ENSMUSG00000078427 UniProt P82979 Q9D1J3 RefSeq (mRNA) NM_033082 NM_025364 RefSeq (protein) NP_149073 NP_079640 NP_001346332 NP_001346333 NP_001346334 NP_001346335 NP_001346336 Location (UCSC) n/a Chr 10: 128.82 – 128.88 Mb PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

SAP domain-containing ribonucleoprotein is a protein that in humans is encoded by the SARNP gene. ^{[4] [5] [6]}

References

1. GRCm38: Ensembl release 89: ENSMUSG00000078427 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Choong ML, Tan LK, Lo SL, Ren EC, Ou K, Ong SE, Liang RC, Seow TK, Chung MC (May 2001). "An integrated approach in the discovery and characterization of a novel nuclear protein over-expressed in liver and pancreatic tumors". FEBS Lett. 496 (2–3): 109–16. Bibcode:2001FEBSL.496..109C. doi: 10.1016/S0014-5793(01)02409-7 . PMID   11356193. S2CID   24122700.
5. Fukuda S, Wu DW, Stark K, Pelus LM (Mar 2002). "Cloning and characterization of a proliferation-associated cytokine-inducible protein, CIP29". Biochem Biophys Res Commun. 292 (3): 593–600. doi:10.1006/bbrc.2002.6680. PMID   11922608.
6. "Entrez Gene: CIP29 cytokine induced protein 29 kDa".

External links

• Human SARNP genome location and SARNP gene details page in the UCSC Genome Browser .

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC   310934 . PMID   11042152.
• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi: 10.1016/S0960-9822(01)00650-9 . PMID   11790298. S2CID   14132033.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Lehner B, Semple JI, Brown SE, et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID   14667819.
• Navakauskiene R, Treigyte G, Gineitis A, Magnusson KE (2004). "Identification of apoptotic tyrosine-phosphorylated proteins after etoposide or retinoic acid treatment". Proteomics. 4 (4): 1029–41. doi:10.1002/pmic.200300671. PMID   15048984. S2CID   26389150.
• Hashii Y, Kim JY, Sawada A, et al. (2004). "A novel partner gene CIP29 containing a SAP domain with MLL identified in infantile myelomonocytic leukemia". Leukemia. 18 (9): 1546–8. doi:10.1038/sj.leu.2403450. PMID   15284855. S2CID   23982148.
• Leaw CL, Ren EC, Choong ML (2004). "Hcc-1 is a novel component of the nuclear matrix with growth inhibitory function". Cell. Mol. Life Sci. 61 (17): 2264–73. doi: 10.1007/s00018-004-4205-x . PMC   11138947 . PMID   15338056. S2CID   19729441.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID   15635413. S2CID   4344740.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Sugiura T, Sakurai K, Nagano Y (2007). "Intracellular characterization of DDX39, a novel growth-associated RNA helicase". Exp. Cell Res. 313 (4): 782–90. doi:10.1016/j.yexcr.2006.11.014. PMID   17196963.