SDF4

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SDF4
Identifiers
Aliases	SDF4 , Cab45, SDF-4, stromal cell derived factor 4
External IDs	OMIM: 614282 MGI: 108079 HomoloGene: 32121 GeneCards: SDF4
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1p36.33 Start 1,216,909 bp [1] End 1,232,067 bp [1]
Gene location (Mouse) Chr. Chromosome 4 (mouse) [2] Band 4|4 E2 Start 156,077,329 bp [2] End 156,098,067 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium thoracic aorta ascending aorta cardia right coronary artery body of stomach trachea pylorus nipple fundus Top expressed in molar supraoptic nucleus spermatocyte calvaria right lung lobe duodenum superior frontal gyrus ascending aorta blood crypt of lieberkuhn of small intestine More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding identical protein binding calcium ion binding Cellular component cell projection extracellular exosome bleb late endosome Golgi lumen cytoplasm membrane plasma membrane Golgi apparatus endoplasmic reticulum Biological process UV protection zymogen granule exocytosis response to ethanol cerebellum development calcium-ion regulated exocytosis exocytosis fat cell differentiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51150 20318 Ensembl ENSG00000078808 ENSMUSG00000029076 UniProt Q9BRK5 Q61112 RefSeq (mRNA) NM_016176 NM_016547 NM_011341 NM_001302467 NM_001302468 NM_001302469 RefSeq (protein) NP_057260 NP_057631 NP_001289396 NP_001289397 NP_001289398 NP_035471 Location (UCSC) Chr 1: 1.22 – 1.23 Mb Chr 4: 156.08 – 156.1 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

45 kDa calcium-binding protein is a protein that in humans is encoded by the SDF4 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000078808 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000029076 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Koivu T, Laitinen S, Riento K, Olkkonen VM (Sep 1997). "Sequence of a human cDNA encoding Cab45, a Ca2+-binding protein with six EF-hand motifs". DNA Seq. 7 (3–4): 217–20. doi:10.3109/10425179709034038. PMID   9254016.
6. Scherer PE, Lederkremer GZ, Williams S, Fogliano M, Baldini G, Lodish HF (May 1996). "Cab45, a novel (Ca2+)-binding protein localized to the Golgi lumen". J Cell Biol. 133 (2): 257–68. doi:10.1083/jcb.133.2.257. PMC   2120788 . PMID   8609160.
7. "Entrez Gene: SDF4 stromal cell derived factor 4".

Further reading

• Honoré B, Vorum H (2000). "The CREC family, a novel family of multiple EF-hand, low-affinity Ca(2+)-binding proteins localised to the secretory pathway of mammalian cells". FEBS Lett. 466 (1): 11–8. doi: 10.1016/S0014-5793(99)01780-9 . PMID   10648803.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi: 10.1093/dnares/12.2.117 . PMID   16303743.
• Lam PP, Hyvärinen K, Kauppi M, et al. (2007). "A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini". Mol. Biol. Cell. 18 (7): 2473–80. doi:10.1091/mbc.E06-10-0950. PMC   1924827 . PMID   17442889.