SEC14L1

SEC14L1
Identifiers
Aliases	SEC14L1 , PRELID4A, SEC14L, SEC14 like lipid binding 1
External IDs	OMIM: 601504 MGI: 1921386 HomoloGene: 37719 GeneCards: SEC14L1
Gene location (Human)
Chr.	Chromosome 17 (human)
End	77,217,101 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	117,050,094 bp
RNA expression pattern
	Top expressed in
	internal globus pallidus; ; blood; ; inferior olivary nucleus; ; lower lobe of lung; ; right lung; ; pericardium; ; olfactory bulb; ; sperm; ; Region I of hippocampus proper; ; superficial temporal artery;
	Top expressed in
	submandibular gland; ; superior frontal gyrus; ; mirror; ; molar; ; entorhinal cortex; ; spermatid; ; cerebellar cortex; ; lacrimal gland; ; parotid gland; ; hippocampus proper;
	More reference expression data
	n/a
Gene ontology
Molecular function	RIG-I binding ; protein binding ; molecular function regulator ;
Cellular component	cytoplasm ; Golgi apparatus ; nucleoplasm ; cytosol ;
Biological process	negative regulation of signal transduction ; innate immune response ; negative regulation of RIG-I signaling pathway ; choline transport ; immune system process ;
	Sources:Amigo / QuickGO
Orthologs
	6397
	74136
	ENSG00000129657
	ENSMUSG00000020823
	Q92503
	A8Y5H7
NM_003003 ; NM_001039573 ; NM_001143998 ; NM_001143999 ; NM_001144001 ;
	NM_001204408 ; NM_001204410
	NM_001166506 ; NM_001166507 ; NM_028777 ; NM_001363165
NP_001034662 ; NP_001137470 ; NP_001137471 ; NP_001137473 ; NP_001191337 ;
	NP_001191339 ; NP_002994
	NP_001159978 ; NP_001159979 ; NP_083053 ; NP_001350094
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 14, 2022

SEC14-like protein 1 is a protein that in humans is encoded by the SEC14L1 gene.^[5]^[6]

The protein encoded by this gene belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system.^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000129657 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020823 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Chinen K, Takahashi E, Nakamura Y (Sep 1996). "Isolation and mapping of a human gene (SEC14L), partially homologous to yeast SEC14, that contains a variable number of tandem repeats (VNTR) site in its 3' untranslated region". Cytogenet Cell Genet. 73 (3): 218–23. doi:10.1159/000134342. PMID 8697811.
1 2 "Entrez Gene: SEC14L1 SEC14-like 1 (S. cerevisiae)".

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146 . PMID 9110174.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Kalikin LM, Bugeaud EM, Palmbos PL, et al. (2002). "Genomic characterization of human SEC14L1 splice variants within a 17q25 candidate tumor suppressor gene region and identification of an unrelated embedded expressed sequence tag" (PDF). Mamm. Genome. 12 (12): 925–9. doi:10.1007/s00335-001-2073-3. hdl: 2027.42/42124 . PMID 11707779. S2CID 1547107.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000129657 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020823 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8697811-5] Chinen K, Takahashi E, Nakamura Y (Sep 1996). "Isolation and mapping of a human gene (SEC14L), partially homologous to yeast SEC14, that contains a variable number of tandem repeats (VNTR) site in its 3' untranslated region". Cytogenet Cell Genet. 73 (3): 218–23. doi:10.1159/000134342. PMID 8697811.

[entrez-6] 1 2 "Entrez Gene: SEC14L1 SEC14-like 1 (S. cerevisiae)".

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SEC14L1

Related Research Articles

References

Further reading