SEPT11

SEPTIN11
Identifiers
Aliases	SEPTIN11 , septin 11, SEPT11
External IDs	OMIM: 612887; MGI: 1277214; HomoloGene: 56800; GeneCards: SEPTIN11; OMA:SEPTIN11 - orthologs
Gene location (Human) Chr. Chromosome 4 (human) [1] Band 4q21.1 Start 76,949,751 bp [1] End 77,040,384 bp [1]
Gene location (Mouse) Chr. Chromosome 5 (mouse) [2] Band 5 E2|5 47.29 cM Start 93,241,296 bp [2] End 93,324,306 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone ganglionic eminence Achilles tendon stromal cell of endometrium sural nerve epithelium of colon periodontal fiber decidua Brodmann area 9 right frontal lobe Top expressed in Gonadal ridge maxillary prominence mandibular prominence dermis tail of embryo abdominal wall ventricular zone genital tubercle renal corpuscle atrioventricular valve More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding GTP binding protein binding GTPase activity molecular adaptor activity Cellular component cytoplasm axon cell junction dendritic spine cell projection synapse cytoskeleton stress fiber postsynapse glutamatergic synapse GABA-ergic synapse postsynaptic specialization of symmetric synapse septin ring microtubule cytoskeleton septin complex septin filament array Biological process cell cycle protein heterooligomerization cell division regulation of synapse organization mitotic cytokinesis septin ring assembly cilium assembly cytoskeleton-dependent cytokinesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55752 52398 Ensembl ENSG00000138758 ENSMUSG00000058013 UniProt Q9NVA2 Q8C1B7 RefSeq (mRNA) NM_001306147 NM_018243 NM_001009818 NM_001310669 NM_001310671 NM_001347377 RefSeq (protein) NP_001293076 NP_060713 NP_001009818 NP_001297598 NP_001297600 NP_001334306 Location (UCSC) Chr 4: 76.95 – 77.04 Mb Chr 5: 93.24 – 93.32 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Septin-11 is a protein that in humans is encoded by the SEPT11 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000138758 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000058013 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Kojima K, Sakai I, Hasegawa A, Niiya H, Azuma T, Matsuo Y, Fujii N, Tanimoto M, Fujita S (May 2004). "FLJ10849, a septin family gene, fuses MLL in a novel leukemia cell line CNLBC1 derived from chronic neutrophilic leukemia in transformation with t(4;11)(q21;q23)". Leukemia. 18 (5): 998–1005. doi:10.1038/sj.leu.2403334. PMID   14999297. S2CID   7182039.
6. Kim DS, Hubbard SL, Peraud A, Salhia B, Sakai K, Rutka JT (May 2004). "Analysis of mammalian septin expression in human malignant brain tumors". Neoplasia. 6 (2): 168–78. doi:10.1593/neo.03310. PMC   1502092 . PMID   15140406.
7. "Entrez Gene: SEPT11 septin 11".

Further reading

• Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (January 2002). "Directed proteomic analysis of the human nucleolus". Current Biology. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi: 10.1016/S0960-9822(01)00650-9 . PMID   11790298. S2CID   14132033.
• Wistow G, Bernstein SL, Wyatt MK, Fariss RN, Behal A, Touchman JW, Bouffard G, Smith D, Peterson K (June 2002). "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants". Molecular Vision. 8: 205–20. PMID   12107410.
• Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR, Vandekerckhove J (May 2003). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nature Biotechnology. 21 (5): 566–9. doi:10.1038/nbt810. PMID   12665801. S2CID   23783563.
• Hanai N, Nagata K, Kawajiri A, Shiromizu T, Saitoh N, Hasegawa Y, Murakami S, Inagaki M (June 2004). "Biochemical and cell biological characterization of a mammalian septin, Sept11". FEBS Letters. 568 (1–3): 83–8. doi:10.1016/j.febslet.2004.05.030. PMID   15196925. S2CID   11315113.
• Nagata K, Asano T, Nozawa Y, Inagaki M (December 2004). "Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11". The Journal of Biological Chemistry. 279 (53): 55895–904. doi: 10.1074/jbc.M406153200 . PMID   15485874.
• Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (January 2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID   15635413. S2CID   4344740.
• Sudo K, Ito H, Iwamoto I, Morishita R, Asano T, Nagata K (October 2007). "SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling". Human Mutation. 28 (10): 1005–13. doi:10.1002/humu.20554. PMID   17546647. S2CID   40174453.
• Xin X, Pache M, Zieger B, Bartsch I, Prünte C, Flammer J, Meyer P (November 2007). "Septin expression in proliferative retinal membranes". The Journal of Histochemistry and Cytochemistry. 55 (11): 1089–94. doi:10.1369/jhc.7A7188.2007. PMC   3957527 . PMID   17625225.