SEZ6

SEZ6
Identifiers
Aliases	SEZ6 , BSRPC, seizure related 6 homolog
External IDs	OMIM: 616666 MGI: 104745 HomoloGene: 10948 GeneCards: SEZ6
Gene location (Human)
Chr.	Chromosome 17 (human)
End	29,006,440 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	77,869,874 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; nucleus accumbens; ; caudate nucleus; ; putamen; ; prefrontal cortex; ; cingulate gyrus; ; amygdala; ; Brodmann area 9; ; hypothalamus; ; hippocampus proper;
	Top expressed in
	olfactory tubercle; ; superior frontal gyrus; ; nucleus accumbens; ; subiculum; ; entorhinal cortex; ; globus pallidus; ; ganglionic eminence; ; hippocampus proper; ; dorsal tegmental nucleus; ; medial geniculate nucleus;
	More reference expression data
	n/a
Orthologs
	124925
	20370
	ENSG00000063015
	ENSMUSG00000000632
	Q53EL9
	Q7TSK2
	NM_001098635 ; NM_001290202 ; NM_178860
	NM_001291225 ; NM_021286
	NP_001092105 ; NP_001277131 ; NP_849191
	NP_001278154 ; NP_067261
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 14, 2022

Seizure protein 6 homolog is a protein that in humans is encoded by the SEZ6 gene.^[5]^[6]

Related Research Articles

Heat shock 70 kDa protein 14 also known as HSP70-like protein 1 or heat shock protein HSP60 is a protein that in humans is encoded by the HSPA14 gene.

MMS19 nucleotide excision repair protein homolog is a protein that in humans is encoded by the MMS19 gene.

Protein SGT1 is a protein that in humans is encoded by the ECD gene.

Probable cation-transporting ATPase 13A3 is an enzyme that in humans is encoded by the ATP13A3 gene.

Solute carrier family 2, facilitated glucose transporter member 6 is a protein that in humans is encoded by the SLC2A6 gene.

tRNA wybutosine-synthesizing protein 2 homolog is a protein that in humans is encoded by the TRMT12 gene.

Zinc finger protein 64 homolog, isoforms 1 and 2 is a protein that in humans is encoded by the ZFP64 gene.

Vacuolar protein sorting-associated protein 52 homolog is a protein that in humans is encoded by the VPS52 gene.

Spermatogenesis-defective protein 39 homolog is a protein that in humans is encoded by the VIPAS39 gene. This protein is involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2. Alternative splicing results in multiple transcript variants.

Sodium-coupled neutral amino acid transporter 1 is a protein that in humans is encoded by the SLC38A1 gene.

Iron-sulfur cluster assembly 1 homolog, mitochondrial is an evolutionarily highly conserved protein for the biogenesis of iron-sulfur cluster across species. In humans it is encoded by the ISCA1 gene.

RWD domain-containing protein 2B is a protein that in humans is encoded by the RWDD2B gene.

Triokinase/FMN cyclase is an enzyme that in humans is encoded by the DAK gene.

COMM domain-containing protein 9 is a protein that in humans is encoded by the COMMD9 gene.

Mitochondrial import inner membrane translocase subunit Tim22 is an enzyme that in humans is encoded by the TIMM22 gene.

Non-SMC element 4 homolog A is a protein that in humans is encoded by the NSMCE4A gene.

COMM domain-containing protein 4 is a protein that in humans is encoded by the COMMD4 gene.

DnaJ homolog subfamily C member 28 is a protein that in humans is encoded by the DNAJC28 gene. It's a member of chaperone DnaJ family. The family is also known as Hsp40.

Zinc phosphodiesterase ELAC protein 1 is an enzyme that in humans is encoded by the ELAC1 gene.

Tetratricopeptide repeat protein 4 is a protein that in humans is encoded by the TTC4 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000063015 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000000632 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Yu ZL, Jiang JM, Wu DH, Xie HJ, Jiang JJ, Zhou L, Peng L, Bao GS (January 2007). "Febrile seizures are associated with mutation of seizure-related (SEZ) 6, a brain-specific gene". Journal of Neuroscience Research. 85 (1): 166–72. doi:10.1002/jnr.21103. PMID 17086543. S2CID 24331881.
↑ "Entrez Gene: SEZ6 seizure related 6 homolog (mouse)".

Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.
Kim MH, Gunnersen JM, Tan SS (October 2002). "Localized expression of the seizure-related gene SEZ-6 in developing and adult forebrains". Mechanisms of Development. 118 (1–2): 171–4. doi: 10.1016/S0925-4773(02)00238-1 . PMID 12351182. S2CID 16791550.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Shimizu-Nishikawa K, Kajiwara K, Sugaya E (November 1995). "Cloning and characterization of seizure-related gene, SEZ-6". Biochemical and Biophysical Research Communications. 216 (1): 382–9. doi:10.1006/bbrc.1995.2635. PMID 7488116.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000063015 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000000632 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid17086543-5] Yu ZL, Jiang JM, Wu DH, Xie HJ, Jiang JJ, Zhou L, Peng L, Bao GS (January 2007). "Febrile seizures are associated with mutation of seizure-related (SEZ) 6, a brain-specific gene". Journal of Neuroscience Research. 85 (1): 166–72. doi:10.1002/jnr.21103. PMID 17086543. S2CID 24331881.

[entrez-6] "Entrez Gene: SEZ6 seizure related 6 homolog (mouse)".

[1]

[2]

[3]

[4]

[5]

[6]

SEZ6

Related Research Articles

References

Further reading