SEZ6

SEZ6
Identifiers
Aliases	SEZ6 , BSRPC, seizure related 6 homolog
External IDs	OMIM: 616666; MGI: 104745; HomoloGene: 10948; GeneCards: SEZ6; OMA:SEZ6 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17q11.2 Start 28,954,901 bp [1] End 29,006,440 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11 B5|11 46.74 cM Start 77,821,626 bp [2] End 77,869,874 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence right hemisphere of cerebellum nucleus accumbens caudate nucleus putamen prefrontal cortex right frontal lobe cingulate gyrus anterior cingulate cortex amygdala Top expressed in olfactory tubercle superior frontal gyrus nucleus accumbens subiculum CA3 field perirhinal cortex primary visual cortex entorhinal cortex dentate gyrus of hippocampal formation granule cell anterior amygdaloid area More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 124925 20370 Ensembl ENSG00000063015 ENSMUSG00000000632 UniProt Q53EL9 Q7TSK2 RefSeq (mRNA) NM_001098635 NM_001290202 NM_178860 NM_001291225 NM_021286 RefSeq (protein) NP_001092105 NP_001277131 NP_849191 NP_001278154 NP_067261 Location (UCSC) Chr 17: 28.95 – 29.01 Mb Chr 11: 77.82 – 77.87 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Seizure protein 6 homolog is a protein that in humans is encoded by the SEZ6 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000063015 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000000632 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Yu ZL, Jiang JM, Wu DH, Xie HJ, Jiang JJ, Zhou L, Peng L, Bao GS (January 2007). "Febrile seizures are associated with mutation of seizure-related (SEZ) 6, a brain-specific gene". Journal of Neuroscience Research. 85 (1): 166–72. doi:10.1002/jnr.21103. PMID   17086543. S2CID   24331881.
6. "Entrez Gene: SEZ6 seizure related 6 homolog (mouse)".

Further reading

• Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Kim MH, Gunnersen JM, Tan SS (October 2002). "Localized expression of the seizure-related gene SEZ-6 in developing and adult forebrains". Mechanisms of Development. 118 (1–2): 171–4. doi:10.1016/S0925-4773(02)00238-1. PMID   12351182. S2CID   16791550.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Shimizu-Nishikawa K, Kajiwara K, Sugaya E (November 1995). "Cloning and characterization of seizure-related gene, SEZ-6". Biochemical and Biophysical Research Communications. 216 (1): 382–9. doi:10.1006/bbrc.1995.2635. PMID   7488116.